{"id":"W3004418786","doi":"10.1152/ajplung.00128.2019","title":"PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Oesterreichische Nationalbank; University College London; Austrian Science Fund; Deutsche Forschungsgemeinschaft; Österreichischen Akademie der Wissenschaften","keywords":"Transdifferentiation; Myofibroblast; Biology; Pathology; Parenchyma; Fibrosis; Mesenchymal stem cell; Desmin; SMA*; Platelet-derived growth factor receptor; Platelet-derived growth factor; Lung; Idiopathic pulmonary fibrosis; Cell biology; Cancer research; Growth factor; Receptor; Vimentin; Immunology; Medicine; Stem cell; Immunohistochemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001779291,0.0001199027,0.0001343689,0.0003513947,0.0001247418,0.0002588123,0.00009510198,0.0002629669,0.0007135651],"category_scores_gemma":[0.0001624696,0.0001247638,0.0001171258,0.0001790391,0.0001894918,0.0001739988,0.0001554678,0.0002356889,0.0003115816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000059072,"about_ca_system_score_gemma":0.00009276284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001768888,"about_ca_topic_score_gemma":0.000366217,"domain_scores_codex":[0.9998536,0.00004073205,0.00001177167,0.00002510401,0.00003642068,0.00003221455],"domain_scores_gemma":[0.9998983,0.0000209605,0.00003034805,0.00001305105,0.00001450675,0.00002276111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007216338,0.000008609487,0.001652683,0.00001576185,0.000001869578,0.0000584621,0.00003212361,0.00001816801,0.9967852,0.00007325081,0.000004569692,0.001277182],"study_design_scores_gemma":[0.00002084498,0.0008242177,0.2146341,0.00002588639,0.000041006,0.004740133,0.0004510652,0.00162329,0.774119,0.000327899,0.003182624,0.00001001132],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947979,0.0007867581,0.003551795,0.00001854556,0.000005403587,0.00001631803,0.00007765387,0.00001338281,0.0007321889],"genre_scores_gemma":[0.9939235,0.0005807079,0.004090128,0.00002674139,0.000007654766,0.00002754614,0.0002004226,0.000004417977,0.001138779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007135651,"threshold_uncertainty_score":0.002387106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009906998444314363,"score_gpt":0.2433069831138888,"score_spread":0.2333999846695745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}