{"id":"W3004500391","doi":"10.1101/2020.01.28.20018655","title":"The increase in paraoxonase-1 is associated with a decrease in left ventricular volume in kidney transplant recipients","year":2020,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Paraoxonase enzyme and polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; London Health Sciences Centre; University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"Schulich School of Medicine and Dentistry; Canadian Institutes of Health Research; Schulich School of Medicine and Dentistry, Western University; University of Toronto; Heart and Stroke Foundation of Canada","keywords":"PON1; Internal medicine; Transplantation; Cardiology; Dialysis; Medicine; Kidney transplantation; Arylesterase; Diastole; Chemistry; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002916188,0.0002463143,0.0003495635,0.0002868771,0.0002027686,0.0004427151,0.0001829288,0.0003628264,0.002001727],"category_scores_gemma":[0.0009391641,0.0001473052,0.000263412,0.0002058645,0.0002555161,0.0002360719,0.0002413156,0.0006835581,0.0002227757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001603685,"about_ca_system_score_gemma":0.0001363333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003715868,"about_ca_topic_score_gemma":0.0002442237,"domain_scores_codex":[0.9998348,0.00003955359,0.00001397369,0.0000327898,0.00003655365,0.00004235872],"domain_scores_gemma":[0.998843,0.0001858986,0.000506025,0.00005458726,0.00005741684,0.0003530852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003403488,0.0002815524,0.9752041,0.00002616229,0.0001148845,0.0005455901,0.00008435309,0.0001071805,0.01510014,0.00004524928,0.0001372632,0.004949878],"study_design_scores_gemma":[0.00002389748,0.0006111176,0.9976926,0.000002653251,0.00003377279,0.0005969107,0.00004458392,0.000233093,0.0006327139,0.00003793598,0.00008704908,0.000003683003],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995648,0.0001409272,0.00006820561,0.00002587529,0.000005814109,0.000001636397,0.00002860083,0.000004862074,0.0001593221],"genre_scores_gemma":[0.999714,0.00003044123,0.00003431113,0.00001715212,0.00001666511,0.000002720089,0.00004620617,0.000001506178,0.0001369462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002001727,"threshold_uncertainty_score":0.006696463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0125391611651235,"score_gpt":0.2344729845452873,"score_spread":0.2219338233801638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}