{"id":"W3004562188","doi":"10.1039/c9an02270h","title":"Imaging mass spectrometry allows for neuroanatomic-specific detection of gangliosides in the healthy and diseased brain","year":2020,"lang":"en","type":"review","venue":"The Analyst","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Mass spectrometry imaging; Mass spectrometry; Membrane; Ganglioside; Chemistry; Neuroscience; Biology; Chromatography; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005672608,0.001005048,0.0009298314,0.002669269,0.0002106859,0.0008661646,0.0006345919,0.001182234,0.002665326],"category_scores_gemma":[0.0005425869,0.0002992983,0.0004003813,0.001843407,0.0004574722,0.001396905,0.0006486866,0.001441677,0.003353235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000511694,"about_ca_system_score_gemma":0.0005678902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006071962,"about_ca_topic_score_gemma":0.0009923086,"domain_scores_codex":[0.9997934,0.00002688834,0.00001622047,0.00004578622,0.00009921877,0.00001865398],"domain_scores_gemma":[0.9997836,0.00008835654,0.00002649501,0.000008500646,0.00007173129,0.00002139273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009657695,0.00006241188,0.0003418162,0.009406538,0.0001073571,0.0003171261,0.00004925184,0.0003126886,0.02645381,0.00523731,0.02403557,0.9335794],"study_design_scores_gemma":[0.00001068027,0.0001030361,0.00114092,0.001108187,0.000109336,0.002462117,0.00005175206,0.0002764479,0.01088737,0.002540113,0.9812728,0.00003726186],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003889297,0.9948315,0.001126211,0.0003250136,0.0002919469,0.000007962343,0.00004667076,0.00004152832,0.002940245],"genre_scores_gemma":[0.001860105,0.9943507,0.001255892,0.0002400333,0.0002543239,0.00001315206,0.00007592894,0.000007612205,0.001942313],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002669269,"threshold_uncertainty_score":0.008916438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02750084821698398,"score_gpt":0.3306813448522348,"score_spread":0.3031804966352509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}