{"id":"W3004630265","doi":"10.1016/j.ctrv.2020.101979","title":"Toxicity management with combination chemotherapy and programmed death 1/programmed death ligand 1 inhibitor therapy in advanced lung cancer","year":2020,"lang":"en","type":"review","venue":"Cancer Treatment Reviews","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Merck Sharp and Dohme","keywords":"Medicine; Nivolumab; Pembrolizumab; Atezolizumab; Lung cancer; Chemotherapy; Oncology; Internal medicine; Immunotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003408762,0.00126905,0.003979611,0.0002604247,0.0001153736,0.0001014019,0.0002013412,0.0002993951,0.0001132442],"category_scores_gemma":[0.000005280523,0.0007624097,0.0006624773,0.0008748525,0.0001065256,0.000132131,0.0000373513,0.0003393777,0.000005298074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002994385,"about_ca_system_score_gemma":0.0005573761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004620713,"about_ca_topic_score_gemma":0.0003588651,"domain_scores_codex":[0.9961753,0.0002525238,0.001211022,0.001280749,0.0003928303,0.0006875938],"domain_scores_gemma":[0.9981099,0.00005242117,0.0008166771,0.0006436944,0.00007086706,0.0003064357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001083365,0.0007631206,0.002820012,0.01504154,0.002009893,0.00009572627,0.0002493858,1.577023e-7,0.000007405034,0.00001107132,0.0001857208,0.9777326],"study_design_scores_gemma":[0.01304482,0.002164763,0.0006993756,0.03689497,0.002157124,0.00003327943,0.00002290959,0.000008085197,0.0001068613,0.000003532428,0.9441652,0.0006991067],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001879622,0.9772495,0.00002155528,0.0006372117,0.0002144158,0.01960286,0.00005348768,0.0001118571,0.0002294853],"genre_scores_gemma":[0.0001291055,0.9741659,0.0008071442,0.0005865383,0.0002394231,0.0230109,0.0002698718,0.0001643023,0.0006267737],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9770335,"threshold_uncertainty_score":0.9994827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05420534162604314,"score_gpt":0.3743132348462432,"score_spread":0.3201078932202001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}