{"id":"W3004650032","doi":"10.1038/s41598-020-58731-y","title":"CAPA neuropeptides and their receptor form an anti-diuretic hormone signaling system in the human disease vector, Aedes aegypti","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"University of Toronto; Natural Sciences and Engineering Research Council of Canada; University of Toronto Mississauga; Ontario Ministry of Research, Innovation and Science; Government of Canada","keywords":"Diuretic; Biology; Endocrinology; Neurohormones; Internal medicine; Malpighian tubule system; Neuropeptide; Atrial natriuretic peptide; NPR1; NPR2; Hormone; Pharmacology; Receptor; Natriuretic peptide; Midgut; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103018,0.0001881712,0.0001159334,0.0001113013,0.00007563092,0.0001455169,0.00009875481,0.000172297,0.001785642],"category_scores_gemma":[0.00007832704,0.000105858,0.0001501041,0.00004182997,0.00009064615,0.0001260185,0.00009355835,0.0002980417,0.0003107607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720251,"about_ca_system_score_gemma":0.00008524922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006328066,"about_ca_topic_score_gemma":0.0005785658,"domain_scores_codex":[0.9999245,0.00001417737,0.000004830057,0.00001932463,0.00001378967,0.00002325593],"domain_scores_gemma":[0.9999745,0.000003097148,0.000006971854,0.000002124568,0.000004427542,0.000008980143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001251043,0.00001560212,0.001026313,0.00002626118,0.00000754631,0.00007578798,0.00001142651,0.00003154713,0.9977109,0.00006639997,0.00008304002,0.0008200608],"study_design_scores_gemma":[0.0001585632,0.002256564,0.2487544,0.00005193858,0.0001783176,0.005526374,0.0004865352,0.009469549,0.7186087,0.0002662699,0.0142188,0.00002401598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964572,0.001320554,0.0007734087,0.00009678941,0.00003041156,0.00001739912,0.0005003794,0.00001908505,0.0007848837],"genre_scores_gemma":[0.9954099,0.000591957,0.0009677801,0.00009949067,0.00001151137,0.00002213658,0.0008227782,0.000004070909,0.002070294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001785642,"threshold_uncertainty_score":0.005973518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0500255713478301,"score_gpt":0.2772017342214183,"score_spread":0.2271761628735882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}