{"id":"W3004728280","doi":"10.1016/j.nucmedbio.2020.02.001","title":"Radioimmunotherapy of human pancreatic cancer xenografts in NOD-scid mice with [64Cu]Cu-NOTA-panitumumab F(ab′)2 alone or combined with radiosensitizing gemcitabine and the PARP inhibitor, rucaparib","year":2020,"lang":"en","type":"article","venue":"Nuclear Medicine and Biology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"University of Toronto; Canadian Cancer Society; Canadian Cancer Society Research Institute; Terry Fox Foundation; Cancer Research Society","keywords":"Panitumumab; Medicine; Radioimmunotherapy; Cancer research; Gemcitabine; Nod; Internal medicine; Cancer; KRAS; Colorectal cancer; Immunology; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004025109,0.0008163517,0.0009275533,0.0005317646,0.0003666128,0.0005293722,0.0005434971,0.0007075331,0.001539947],"category_scores_gemma":[0.0001651204,0.0005517175,0.000588599,0.0004359095,0.0004160496,0.0004722995,0.0002205195,0.001429895,0.0004526769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006265604,"about_ca_system_score_gemma":0.0008288638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003904907,"about_ca_topic_score_gemma":0.002940677,"domain_scores_codex":[0.9996436,0.00006542667,0.00002246663,0.0001060553,0.00004781161,0.000114648],"domain_scores_gemma":[0.9998227,0.00002896521,0.00004527817,0.00004279804,0.00001418631,0.00004615139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007426249,0.001588528,0.0003324696,0.00009988445,0.00006704684,0.0001284929,0.0001055092,0.001197412,0.9834707,0.0004223782,0.0006855456,0.004475764],"study_design_scores_gemma":[0.000793172,0.006604075,0.00187435,0.00001344157,0.000110546,0.0003603385,0.00006131182,0.003601182,0.9817337,0.0001047565,0.004727508,0.00001563467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881892,0.001939993,0.002271662,0.0003695265,0.0003483147,0.0001939593,0.001016047,0.0003343912,0.005336875],"genre_scores_gemma":[0.9880311,0.001202799,0.002331902,0.00009902741,0.00004814626,0.0002087051,0.001184625,0.00008998844,0.006803547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003904907,"threshold_uncertainty_score":0.007764339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05013358152487458,"score_gpt":0.3255006893857514,"score_spread":0.2753671078608769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}