{"id":"W3004845447","doi":"10.1186/s13041-019-0536-2","title":"Delayed expression of activity-dependent gating switch in synaptic AMPARs at a central synapse","year":2020,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mental Health Research Canada; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Neuroscience; Gating; Synapse; Postsynaptic potential; Excitatory postsynaptic potential; Postsynaptic Current; Population; Sensory gating; Excitatory synapse; Brainstem; AMPA receptor; Synaptic plasticity; Long-term potentiation; Bursting; Chemistry; Biology; Inhibitory postsynaptic potential; NMDA receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006038536,0.0001861397,0.0001621314,0.0001265322,0.00006748836,0.0001845465,0.0002011746,0.0001664657,0.001017598],"category_scores_gemma":[0.0001650467,0.00009119105,0.0001817367,0.00007767776,0.0001712811,0.000151317,0.0001763242,0.0004356592,0.0001985881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001845354,"about_ca_system_score_gemma":0.00008762391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002707661,"about_ca_topic_score_gemma":0.0002996497,"domain_scores_codex":[0.9999344,0.000004008612,0.000007621429,0.00001392722,0.00001838898,0.00002166582],"domain_scores_gemma":[0.9998657,0.00001479764,0.00004917436,0.00001933356,0.000017531,0.00003341071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002598662,0.000003387498,0.0001167233,0.00000539976,0.000001166734,0.00001945506,0.000002631269,0.00001013204,0.9995396,0.00002240169,0.000004391045,0.0002486512],"study_design_scores_gemma":[0.000009970185,0.0002414463,0.03734866,0.000005352512,0.00001129337,0.0002865928,0.00002910822,0.00103798,0.9605465,0.0001127573,0.0003644653,0.00000581837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99764,0.000177481,0.001628902,0.00001917313,0.00001029516,0.000006717734,0.00009878325,0.00004722153,0.000371353],"genre_scores_gemma":[0.9988025,0.00007534677,0.0005064574,0.000015556,0.000003385517,0.00001029961,0.00007602546,0.000007535305,0.0005029411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001017598,"threshold_uncertainty_score":0.0034042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04140005626274482,"score_gpt":0.3177703702156596,"score_spread":0.2763703139529148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}