{"id":"W3004873674","doi":"10.3324/haematol.2019.220962","title":"Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children’s Oncology Group","year":2020,"lang":"en","type":"article","venue":"Haematologica","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute","keywords":"Bortezomib; Medicine; Internal medicine; Chemotherapy; Randomized controlled trial; Myeloid leukemia; Oncology; Induction chemotherapy; Multiple myeloma; Leukemia; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002881373,0.0006547059,0.001728574,0.00005866294,0.000319518,0.00007520334,0.0004815269,0.0003404483,0.0001778859],"category_scores_gemma":[0.000193332,0.000257149,0.0003047026,0.0002538718,0.0004847285,0.0001070053,0.0001190987,0.0005699922,0.00002730468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001649389,"about_ca_system_score_gemma":0.001532782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009522591,"about_ca_topic_score_gemma":0.000305354,"domain_scores_codex":[0.9965245,0.0001178458,0.0006530553,0.001218527,0.0006642603,0.0008218487],"domain_scores_gemma":[0.997291,0.0005325047,0.0004549721,0.001078018,0.0002067107,0.0004368245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05492407,0.0007763179,0.8624781,0.00007251358,0.0160077,0.008219437,0.004841451,0.000008693867,0.00661853,0.0004244471,0.01402792,0.03160085],"study_design_scores_gemma":[0.07259815,0.04658398,0.7633582,0.0001630868,0.004042692,0.01503273,0.001614739,0.0002754772,0.06206899,0.0002817426,0.03236258,0.001617681],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9414054,0.0001175051,0.002911237,0.04845302,0.00005793258,0.005480774,0.0009455896,0.0003228991,0.0003056021],"genre_scores_gemma":[0.9555148,0.0004298998,0.02710429,0.0132342,0.0004546249,0.001513101,0.001002669,0.0001489021,0.0005975536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09911992,"threshold_uncertainty_score":0.9999881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054202687182094,"score_gpt":0.2999462043802187,"score_spread":0.2794041775083978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}