{"id":"W3004879944","doi":"10.1038/s41467-019-14091-4","title":"Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Branco Weiss Fellowship – Society in Science; Innosuisse - Schweizerische Agentur für Innovationsförderung; École Polytechnique Fédérale de Lausanne; Natural Sciences and Engineering Research Council of Canada; British Heart Foundation","keywords":"Inositol; Calcification; Chemistry; Inositol phosphate; In vitro; Calcium; Phosphate; Pharmacokinetics; Biochemistry; Toxicity; Pharmacology; Internal medicine; Biology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004565086,0.0001224832,0.0002260828,0.00004380707,0.0001138683,0.000009190416,0.0001820452,0.0001663271,0.000009750472],"category_scores_gemma":[0.00007585395,0.0001005703,0.0000657475,0.0004628755,0.0001184518,0.00008399021,0.00005463666,0.0003655065,0.00001067363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003623493,"about_ca_system_score_gemma":0.00006705346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004072698,"about_ca_topic_score_gemma":0.0000166074,"domain_scores_codex":[0.9992576,0.00005648823,0.0002107123,0.0001667744,0.0002006464,0.0001077556],"domain_scores_gemma":[0.998724,0.00006705635,0.000132693,0.0007802207,0.0001898518,0.0001061402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00132211,0.00422187,0.1756411,0.0001563629,0.001647388,0.00001081181,0.005578778,0.00003202519,0.708557,0.006364108,0.09325352,0.003214912],"study_design_scores_gemma":[0.02347951,0.001714458,0.1378599,0.0002248141,0.001507964,0.00002101331,0.002120286,0.002315541,0.6970331,0.0002416501,0.132689,0.0007927816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8837634,0.08288567,0.0009782003,0.02723292,0.00002703603,0.001422443,0.00009499187,0.0001435559,0.003451772],"genre_scores_gemma":[0.9894784,0.002211937,0.006183567,0.00109157,0.00001005165,0.0001026258,0.0008831186,0.0000177765,0.00002093572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.105715,"threshold_uncertainty_score":0.4101138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01743203785758324,"score_gpt":0.2893055499864522,"score_spread":0.271873512128869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}