{"id":"W3004889210","doi":"10.1136/rmdopen-2019-001149","title":"Effects of ustekinumab on spondylitis-associated endpoints in TNFi-naïve active psoriatic arthritis patients with physician-reported spondylitis: pooled results from two phase 3, randomised, controlled trials","year":2020,"lang":"en","type":"article","venue":"RMD Open","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation; University of Toronto","funders":"Janssen Research and Development; Janssen Scientific Affairs","keywords":"Medicine; Psoriatic arthritis; Ustekinumab; Spondylitis; Ankylosing spondylitis; Psoriasis; Physical therapy; Randomized controlled trial; Enthesitis; Internal medicine; Dermatology; Disease; Adalimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01098197,0.002098314,0.009928424,0.001207031,0.0004262548,0.001945749,0.001073151,0.002099417,0.002370132],"category_scores_gemma":[0.009222196,0.001104388,0.01319167,0.001668069,0.0009441035,0.001316185,0.0007040157,0.001953739,0.0002559591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009695939,"about_ca_system_score_gemma":0.001208393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001370953,"about_ca_topic_score_gemma":0.003995478,"domain_scores_codex":[0.9935839,0.003668291,0.00124165,0.0005899366,0.0006497511,0.0002664954],"domain_scores_gemma":[0.9938883,0.00287268,0.001988662,0.0003285355,0.0005072374,0.0004146018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.7809008,0.0008314003,0.003333327,0.02881369,0.1471567,0.00009122639,0.0001005133,0.0007746696,0.002086597,0.00007119199,0.0009926988,0.03484715],"study_design_scores_gemma":[0.7504997,0.03272551,0.02150939,0.002111584,0.1888194,0.000164746,0.00009971437,0.0006412868,0.001030585,0.000257782,0.002063997,0.0000762919],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4352605,0.5506579,0.00202263,0.0008685039,0.001511513,0.00391594,0.002964316,0.000247533,0.002551142],"genre_scores_gemma":[0.9072635,0.08431246,0.001712295,0.001050259,0.0008822174,0.002475277,0.001571029,0.00003589437,0.0006970569],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01098197,"threshold_uncertainty_score":0.05807894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02518199339125456,"score_gpt":0.3110070195540225,"score_spread":0.285825026162768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}