{"id":"W3004902055","doi":"10.1016/j.bpj.2019.11.1373","title":"Melatonin Changes Domain Structure and Protects Model Neuronal Membranes Against Damage Caused by Amyloid-Beta","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Membrane; POPC; Biophysics; Melatonin; Chemistry; Lipid raft; Peptide; Sphingomyelin; Lipid bilayer; Amyloid beta; Cell biology; Biochemistry; Biology; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009870887,0.0002112002,0.0001295862,0.0001168511,0.0002112787,0.0002145229,0.0002339548,0.0002456263,0.001034676],"category_scores_gemma":[0.0001630136,0.0001252627,0.0001881995,0.0001041827,0.0002044385,0.0003225743,0.0001497241,0.0004868954,0.0002031324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003017546,"about_ca_system_score_gemma":0.0001861443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001093672,"about_ca_topic_score_gemma":0.0007241471,"domain_scores_codex":[0.9999506,0.00000895401,0.000003595006,0.00001088383,0.000007493051,0.00001846252],"domain_scores_gemma":[0.9998865,0.00001500797,0.00004057954,0.00001559702,0.00001468092,0.00002772652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000498428,0.00002173975,0.0002465013,0.00001726997,0.000008998798,0.00004067323,0.00002377266,0.00003131017,0.9984717,0.00009005963,0.00003128799,0.0005181059],"study_design_scores_gemma":[0.00005110196,0.0002377635,0.008792428,0.000006329546,0.00002381178,0.0001791025,0.00008803219,0.0007959662,0.9885661,0.0002077682,0.001042636,0.000008938681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980599,0.0005896493,0.0006836279,0.00006030208,0.00002164231,0.000004150187,0.000114638,0.00002394347,0.0004421231],"genre_scores_gemma":[0.9985274,0.0003162929,0.0003556047,0.00003080511,0.000004780541,0.000004248796,0.0001697882,0.0000116671,0.0005792929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001093672,"threshold_uncertainty_score":0.003461361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02218485827823558,"score_gpt":0.2326639583421706,"score_spread":0.210479100063935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}