{"id":"W3004941663","doi":"10.1016/j.bbagrm.2020.194501","title":"Riboswitch regulation mechanisms: RNA, metabolites and regulatory proteins","year":2020,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Riboswitch; RNA; Computational biology; Metabolite; Biology; Regulation of gene expression; Gene expression; Regulatory sequence; Gene; Cell biology; Non-coding RNA; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001209045,0.002374224,0.003481145,0.0004841347,0.0005497442,0.0003315353,0.001533085,0.002208594,0.00008511295],"category_scores_gemma":[0.0001712924,0.002218182,0.001648934,0.0007356319,0.0003346101,0.00006579698,0.001173342,0.0007564848,0.0001204054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001590685,"about_ca_system_score_gemma":0.0009523187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001192715,"about_ca_topic_score_gemma":0.000003770039,"domain_scores_codex":[0.990992,0.001320637,0.001866898,0.003324475,0.001205265,0.001290742],"domain_scores_gemma":[0.9941322,0.0000970739,0.001867946,0.00280391,0.0002539773,0.0008448693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009391845,0.0001350751,4.037963e-9,0.001890476,0.0008403865,0.00001461671,0.00005811105,6.001844e-7,0.8708155,0.01251666,0.0003411605,0.1132935],"study_design_scores_gemma":[0.0005581097,0.000633523,0.000007619046,0.001710952,0.001646701,0.0001354118,0.00003564845,0.00001931001,0.8824059,0.009338887,0.1013656,0.002142316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0159269,0.9600322,0.01559261,0.0003947889,0.001025974,0.005589319,0.0007775094,0.0004091205,0.0002515442],"genre_scores_gemma":[0.02141882,0.9453338,0.02610005,0.0004724939,0.001563276,0.001276176,0.00190921,0.0008314239,0.001094803],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1111512,"threshold_uncertainty_score":0.9990867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02060456197131001,"score_gpt":0.2634482725949946,"score_spread":0.2428437106236846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}