{"id":"W3004955791","doi":"10.1016/j.pediatrneurol.2020.02.001","title":"Response to Samanta “Are Ketamine Infusions a Viable Therapeutic Option for Refractory Neonatal Seizures?”","year":2020,"lang":"en","type":"letter","venue":"Pediatric Neurology","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Lidocaine; Levetiracetam; Medicine; Phenytoin; Midazolam; Anesthesia; Ketamine; Dosing; Contraindication; Refractory (planetary science); Population; Epilepsy; Pharmacology; Sedation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001551265,0.0006420623,0.001103297,0.0006886612,0.003696093,0.003291005,0.001808986,0.04752373,0.007812447],"category_scores_gemma":[0.02074495,0.0006067536,0.001009241,0.000801189,0.002340107,0.002669579,0.001191739,0.02971495,0.003988073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004716638,"about_ca_system_score_gemma":0.005401628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006066929,"about_ca_topic_score_gemma":0.01086024,"domain_scores_codex":[0.998353,0.0004064242,0.0002405419,0.0002354841,0.0003723064,0.0003923248],"domain_scores_gemma":[0.9948548,0.002135593,0.0006406621,0.0001367048,0.000896073,0.001336064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001368503,0.00007551028,0.002326151,0.0001051318,0.00004180164,0.02659689,0.0003310797,0.0002176145,0.0003389792,0.004838296,0.953557,0.01143457],"study_design_scores_gemma":[0.0003472247,0.0002543363,0.003812032,0.0008951401,0.0001152577,0.04365736,0.001791417,0.001525608,0.0007243786,0.01903136,0.9276921,0.0001538818],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001038315,0.0007399258,0.0000553862,0.990398,0.004922765,0.00000777231,0.0000347541,0.00001662984,0.002786364],"genre_scores_gemma":[0.01084676,0.001355018,0.0002713171,0.9623839,0.01959142,0.00002888134,0.00002918589,0.00002298177,0.005470452],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04752373,"threshold_uncertainty_score":0.03422177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06017398373456359,"score_gpt":0.345076698196857,"score_spread":0.2849027144622934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}