{"id":"W3005027756","doi":"10.1016/j.cyto.2020.155025","title":"Cross-talk between SUMOylation and ISGylation in response to interferon","year":2020,"lang":"en","type":"article","venue":"Cytokine","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Genome Canada","keywords":"ISG15; SUMO protein; Tetherin; Biology; SAMHD1; Interferon; Downregulation and upregulation; Immune system; Cell biology; Ubiquitin; Gene; Genetics; Cell culture; Viral replication; Reverse transcriptase; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003607766,0.0003062492,0.0003618968,0.0003062951,0.0003005436,0.0005051303,0.0001978181,0.0004065419,0.002230229],"category_scores_gemma":[0.0002064286,0.0001915396,0.0004326915,0.0002231281,0.0002392898,0.0004931822,0.0004794,0.0005246149,0.0003940599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003890069,"about_ca_system_score_gemma":0.0001399162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002158862,"about_ca_topic_score_gemma":0.0003660184,"domain_scores_codex":[0.9998054,0.00003714746,0.00001323089,0.00003393688,0.00003554168,0.0000747831],"domain_scores_gemma":[0.9998789,0.00002129969,0.00002772628,0.0000147389,0.00001889869,0.00003836874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001047133,0.00003185167,0.001798262,0.00005114064,0.00002201003,0.0001617273,0.00003302181,0.0001792789,0.9922501,0.0006434322,0.0001059724,0.003676095],"study_design_scores_gemma":[0.00005210024,0.0003706507,0.1337169,0.00002728989,0.00003972413,0.0006075868,0.0002516261,0.004347927,0.8556105,0.001324155,0.003632034,0.00001951374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887334,0.004878819,0.002446976,0.0003113744,0.0001289154,0.00001530801,0.0001586653,0.00003705756,0.00328942],"genre_scores_gemma":[0.9967682,0.0006968734,0.000423105,0.00008063041,0.00002695804,0.00000840338,0.0001904544,0.000007408689,0.001797918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002230229,"threshold_uncertainty_score":0.007460833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02491914309477005,"score_gpt":0.2892138202439673,"score_spread":0.2642946771491972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}