{"id":"W3005116118","doi":"10.1200/jco.2020.38.15_suppl.e16656","title":"Effect of neoadjuvant immunotherapy and targeted therapies on surgical resection in patients with solid tumors: A systematic review and meta-analysis.","year":2020,"lang":"en","type":"review","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; Western University; Ontario Clinical Oncology Group; McMaster University","funders":"","keywords":"Medicine; Neoadjuvant therapy; Meta-analysis; Immunotherapy; Internal medicine; Oncology; Renal cell carcinoma; Randomized controlled trial; Adverse effect; Hepatocellular carcinoma; Cancer; Surgery; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009566964,0.002302231,0.01762388,0.005570355,0.0004840476,0.002477635,0.001736339,0.002052734,0.003868582],"category_scores_gemma":[0.02024823,0.001217721,0.03595371,0.007404938,0.0005934482,0.001617826,0.001232044,0.001666663,0.0003277745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002092637,"about_ca_system_score_gemma":0.003048855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00622328,"about_ca_topic_score_gemma":0.01494165,"domain_scores_codex":[0.9933664,0.003038228,0.001954617,0.0006855633,0.0007106747,0.0002445734],"domain_scores_gemma":[0.9868013,0.009651588,0.0022158,0.0002866932,0.0008495492,0.0001950751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002031982,0.000022627,0.00299235,0.4637145,0.5197483,0.0001186776,0.00006225813,0.0004252895,0.000191868,0.0001090211,0.0006573,0.009925836],"study_design_scores_gemma":[0.0005921393,0.0001682926,0.003611133,0.0302693,0.9630612,0.00009878042,0.00004214253,0.0001597653,0.0000888858,0.0001697146,0.00171681,0.00002180094],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002971044,0.995504,0.0003279974,0.0001595265,0.0001116262,0.0001675411,0.0005585231,0.0000140989,0.0001856337],"genre_scores_gemma":[0.1415225,0.8533937,0.001534215,0.0008623583,0.0002155976,0.0009663642,0.00110049,0.00002699032,0.0003776962],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01762388,"threshold_uncertainty_score":0.05059552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1004478270739538,"score_gpt":0.4790680609000406,"score_spread":0.3786202338260867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}