{"id":"W3005156440","doi":"10.1097/inf.0000000000002568","title":"Safety, Efficacy and Pharmacokinetics of Anidulafungin in Patients 1 Month to <2 Years of Age With Invasive Candidiasis, Including Candidemia","year":2020,"lang":"en","type":"article","venue":"The Pediatric Infectious Disease Journal","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of California, Los Angeles; Astellas Pharma; University of Alberta; Teva Pharmaceutical Industries; Gilead Sciences; Sanofi; GlaxoSmithKline; Pfizer","keywords":"Anidulafungin; Medicine; Pharmacokinetics; Invasive candidiasis; Fluconazole; Adverse effect; Internal medicine; Antifungal; Dermatology; Micafungin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005855195,0.0001783645,0.000384128,0.00015979,0.0002050841,0.0002466429,0.00009155396,0.0002786897,0.0003630402],"category_scores_gemma":[0.001463894,0.0001070455,0.0002541111,0.0001763775,0.0001456669,0.0002314389,0.0001199999,0.0004673955,0.00009573143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020674,"about_ca_system_score_gemma":0.0002453508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005372292,"about_ca_topic_score_gemma":0.0008213628,"domain_scores_codex":[0.9997653,0.00008787384,0.00002679722,0.00003283546,0.00005442953,0.0000327106],"domain_scores_gemma":[0.9993858,0.0002157321,0.0001933701,0.00002248842,0.00004809054,0.0001344702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.04331032,0.00411999,0.7718765,0.0003144197,0.0003300934,0.003079001,0.0009861421,0.001333119,0.05229168,0.0001137567,0.0009221453,0.1213229],"study_design_scores_gemma":[0.002062045,0.06593607,0.9200974,0.00003830944,0.0002198801,0.00353686,0.0001920609,0.001213089,0.004884624,0.00006089434,0.00173844,0.00002032875],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987264,0.0007563329,0.00007953819,0.00004264846,0.000004747877,0.00001582172,0.00007550905,0.000004159748,0.0002947572],"genre_scores_gemma":[0.9992946,0.0003067567,0.00009893152,0.00005772623,0.00002040129,0.00001641344,0.0001184324,0.000001187024,0.0000855763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005855195,"threshold_uncertainty_score":0.003096581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01333968169241491,"score_gpt":0.26199346099337,"score_spread":0.2486537793009551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}