{"id":"W3005361124","doi":"10.3390/cancers12020374","title":"Autotaxin and Breast Cancer: Towards Overcoming Treatment Barriers and Sequelae","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Memorial University of Newfoundland","funders":"","keywords":"Autotaxin; Breast cancer; Medicine; Cancer; Clinical trial; Adjuvant; Tumor microenvironment; Cancer research; Oncology; Internal medicine; Bioinformatics; Lysophosphatidic acid; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007005526,0.0004003174,0.0008831208,0.00004228108,0.0001028313,0.00005169017,0.000116036,0.0002584147,0.00003609263],"category_scores_gemma":[0.00002292452,0.0003306305,0.0001819896,0.00008548245,0.0001054992,0.000003942784,0.0001024359,0.0001230674,0.000001109995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003873981,"about_ca_system_score_gemma":0.001981828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006602306,"about_ca_topic_score_gemma":0.00004307757,"domain_scores_codex":[0.9987507,0.0000616527,0.0002408422,0.0005969543,0.00008421903,0.0002655933],"domain_scores_gemma":[0.9992948,0.000009353157,0.0001414846,0.0002095834,0.0000220125,0.0003227221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001734698,0.000001173544,0.00001825275,0.001286577,0.0003069525,0.00000918174,0.00009611889,0.000005712864,0.0002440319,0.00001221,0.0003771507,0.9976253],"study_design_scores_gemma":[0.0003696877,0.00005801343,0.000007525427,0.0008440469,0.0005694489,0.0000865459,0.00004449966,0.00001699534,0.000181879,0.000002427735,0.997475,0.0003439001],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001112756,0.9974429,0.00001768323,0.00005171447,0.0003432792,0.000304411,0.0005722016,0.0000159006,0.0001391428],"genre_scores_gemma":[0.0006561182,0.9977597,0.000067432,0.0001603449,0.0009040159,0.0001336891,0.00008397894,0.00005600874,0.0001787159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9972814,"threshold_uncertainty_score":0.9999146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02224463122558146,"score_gpt":0.3042409060045131,"score_spread":0.2819962747789316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}