{"id":"W3005373577","doi":"10.2139/ssrn.3526892","title":"Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds Against <i>Klebsiella pneumoniae</i>","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Klebsiella pneumoniae; Microbiology; Klebsiella; Biology; Antibacterial activity; Bacteria; Genetics; Gene; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002112183,0.0005301976,0.0003966954,0.0002462131,0.00013718,0.0003350948,0.0002939249,0.0003940479,0.002004127],"category_scores_gemma":[0.0002270787,0.0001507245,0.0003651301,0.0002422869,0.0002495773,0.00009943071,0.0001751166,0.0004341125,0.001145141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004087729,"about_ca_system_score_gemma":0.0004746441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001870943,"about_ca_topic_score_gemma":0.002608392,"domain_scores_codex":[0.999687,0.00004475747,0.00002739662,0.00005443035,0.0001346738,0.00005185199],"domain_scores_gemma":[0.9998951,0.00002139115,0.00003478789,0.00001090426,0.00001827175,0.00001954465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005891335,0.00002013615,0.0001152919,0.00002109182,0.000004143362,0.00003203641,0.000003796948,0.00007878178,0.9984306,0.00004438348,0.00007281887,0.001118066],"study_design_scores_gemma":[0.000005108238,0.0001397771,0.0007135006,0.000002352344,0.000008493672,0.000128578,0.00001024259,0.0002556645,0.9976817,0.00001369639,0.00103802,0.000002856802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686344,0.00200673,0.01805303,0.0005951992,0.00009706056,0.0001153073,0.002838081,0.0007441448,0.006916142],"genre_scores_gemma":[0.9754862,0.0008280884,0.01321796,0.0002761915,0.00001383454,0.00003903848,0.002677872,0.0001056495,0.007355129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002004127,"threshold_uncertainty_score":0.00670445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005025630208099595,"score_gpt":0.2354425418015884,"score_spread":0.2304169115934888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}