{"id":"W3005421607","doi":"10.1242/jcs.234047","title":"CLN3 regulates endosomal function by modulating Rab7A–effector interactions","year":2020,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université du Québec à Montréal; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Biology; Effector; Endosome; Cell biology; Function (biology); Computational biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001571751,0.0003204339,0.0001564614,0.0002233274,0.0003014771,0.0003642899,0.0002965477,0.0003200089,0.001263501],"category_scores_gemma":[0.0001863096,0.00007922798,0.0002085921,0.0001320017,0.000241891,0.0002222326,0.0003422205,0.0002661131,0.0005081812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008705835,"about_ca_system_score_gemma":0.0002380207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001243391,"about_ca_topic_score_gemma":0.002498874,"domain_scores_codex":[0.9998778,0.00002462299,0.00001129648,0.00002347264,0.00003108164,0.00003170332],"domain_scores_gemma":[0.999938,0.000008823642,0.00001738826,0.000005070084,0.00001146206,0.00001922697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001781081,0.00001674276,0.0009908811,0.00002431886,0.00000513803,0.0003183647,0.00001795947,0.00009881787,0.9963996,0.0002016717,0.0001350729,0.001613342],"study_design_scores_gemma":[0.00006893258,0.0001262308,0.02201488,0.0000222504,0.00002581121,0.001739094,0.0001619629,0.004401756,0.9645127,0.0007629336,0.006145956,0.00001758563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932173,0.001538121,0.002029344,0.0002064601,0.0000345585,0.00001559112,0.0002422706,0.00009918928,0.002617182],"genre_scores_gemma":[0.9972337,0.0003165906,0.0007318816,0.00006260658,0.000004382291,0.00001085221,0.0002279818,0.00002535488,0.001386692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263501,"threshold_uncertainty_score":0.006316543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00790023293910071,"score_gpt":0.2175006641338701,"score_spread":0.2096004311947694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}