{"id":"W3005671090","doi":"10.3390/biom10020272","title":"Role of an Aromatic–Aromatic Interaction in the Assembly and Trafficking of the Zebrafish Panx1a Membrane Channel","year":2020,"lang":"en","type":"article","venue":"Biomolecules","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Endoplasmic reticulum; Cell biology; Golgi apparatus; Glycosylation; Zebrafish; Transmembrane protein; Transmembrane domain; N-linked glycosylation; Integral membrane protein; Endoplasmic-reticulum-associated protein degradation; Pannexin; Membrane protein; Biology; Chemistry; Unfolded protein response; Biochemistry; Membrane; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001459586,0.00009545257,0.0001397206,0.00002436095,0.00002866423,0.00001051685,0.0002179196,0.00008060126,0.000002126689],"category_scores_gemma":[0.00008528654,0.00005917045,0.0000578867,0.0001109082,0.0001122165,0.000004559578,0.00006608448,0.00005692629,3.916173e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002333014,"about_ca_system_score_gemma":0.00001942293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006212739,"about_ca_topic_score_gemma":0.0001731709,"domain_scores_codex":[0.999261,0.000169085,0.0002168922,0.0001717892,0.0000741593,0.0001070549],"domain_scores_gemma":[0.999604,0.00002577194,0.0001240108,0.0002056453,0.00001421637,0.0000262817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004164503,0.00005780353,0.0002111584,0.00003248482,0.00001997536,8.355293e-7,0.001009703,0.00001488512,0.9956194,0.0000616987,0.00001769178,0.002912739],"study_design_scores_gemma":[0.0004460709,0.0005137306,0.0151615,0.00004406424,0.00002720419,0.00002823106,0.004306683,0.002147116,0.9762462,0.0001307443,0.000825656,0.0001227731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99837,0.0003652818,0.00005079067,0.0007841438,0.00003146028,0.0001591131,0.000007822438,0.000004106145,0.0002273014],"genre_scores_gemma":[0.9994509,0.00003378539,0.00007752023,0.0003529859,0.00004889196,0.000007582373,0.00001766988,0.000008213443,0.00000244213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01937316,"threshold_uncertainty_score":0.2412901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01343000397492085,"score_gpt":0.2425089270335011,"score_spread":0.2290789230585802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}