{"id":"W3005682163","doi":"10.3389/fcell.2020.00070","title":"Emerging Methods for Enhancing Pluripotent Stem Cell Expansion","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; University of Waterloo","keywords":"Microcarrier; Regenerative medicine; Induced pluripotent stem cell; Stem cell; Tissue engineering; Biomedical engineering; Computer science; Biochemical engineering; Nanotechnology; Cell culture; Cell biology; Embryonic stem cell; Materials science; Biology; Medicine; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006457573,0.0008519523,0.000774716,0.002352245,0.0002219666,0.0008945381,0.0006034502,0.0008283601,0.002715533],"category_scores_gemma":[0.0005517506,0.0003652751,0.0006555948,0.0015836,0.0003813046,0.001109194,0.0007235893,0.001459187,0.001855304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004572509,"about_ca_system_score_gemma":0.0005649964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000531082,"about_ca_topic_score_gemma":0.0007922616,"domain_scores_codex":[0.999597,0.00004843692,0.00003674324,0.00006457909,0.0002216542,0.00003159432],"domain_scores_gemma":[0.9998109,0.00008531599,0.00003099269,0.000007981557,0.00005475554,0.00001016351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004233588,0.00009557366,0.0001963763,0.02673997,0.00008983042,0.0002809655,0.0001126266,0.0009273346,0.04498337,0.01508564,0.01198427,0.8994617],"study_design_scores_gemma":[0.00001570565,0.0001737136,0.0006562759,0.001970344,0.0001176612,0.001039868,0.00005595464,0.0005021808,0.02968071,0.003033303,0.9627154,0.00003887437],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001034962,0.9908528,0.003215156,0.0002220371,0.0003211637,0.00002975363,0.00006024653,0.00004110796,0.004222732],"genre_scores_gemma":[0.004142905,0.9915456,0.002259882,0.0001923553,0.0001143794,0.00004223909,0.00008087102,0.000007963762,0.001613722],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002715533,"threshold_uncertainty_score":0.009084344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03155815104381371,"score_gpt":0.3366142764428667,"score_spread":0.305056125399053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}