{"id":"W3005750719","doi":"10.1083/jcb.201906147","title":"CDK1 couples proliferation with protein synthesis","year":2020,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Weill Cornell Medical College; RIKEN; Imperial College London; Danmarks Frie Forskningsfond; Lundbeckfonden; Hebrew University of Jerusalem; University of Oxford; University of Ottawa; McGill University; Deutsche Forschungsgemeinschaft; Deutsches Krebsforschungszentrum","keywords":"Cyclin-dependent kinase 1; Protein biosynthesis; Translation (biology); Cell biology; Eukaryotic translation; Cell cycle; Phosphorylation; Cell growth; EIF4E; Biology; Kinase; Messenger RNA; Chemistry; Cell; Molecular biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001610464,0.0000615978,0.00009022337,0.00001112026,0.00004801993,0.000007014858,0.0001651949,0.00005246102,0.00002370682],"category_scores_gemma":[0.00004243806,0.00003248703,0.00003219142,0.00004285986,0.00006929887,0.000002304727,0.00001699077,0.00007349513,0.000004210991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004895381,"about_ca_system_score_gemma":0.00009182241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000210447,"about_ca_topic_score_gemma":0.000003011832,"domain_scores_codex":[0.9995642,0.00009127425,0.0001498848,0.00006723163,0.00004734069,0.00008004573],"domain_scores_gemma":[0.9995468,0.00001257364,0.0001788633,0.0001040588,0.0001173869,0.00004036021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003205677,0.00001659151,0.0001526637,0.000005938399,0.00002665885,5.08353e-7,0.00005907222,0.0001237185,0.9976318,0.00004452333,0.0002762261,0.001341685],"study_design_scores_gemma":[0.0002159869,0.0007613269,0.0001507343,0.000005582824,0.00002892538,0.00001770044,0.0001014803,0.00006162585,0.9707605,0.00003075354,0.02781105,0.00005431045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904577,0.0009408657,0.005690848,0.002243869,0.00002191031,0.0001114442,0.00000394651,0.00000202167,0.0005274102],"genre_scores_gemma":[0.9984486,0.0003354003,0.0004859734,0.0003596997,0.000264354,0.000007767025,0.000003363618,0.000006918943,0.00008793477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02753483,"threshold_uncertainty_score":0.1324783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259144859961713,"score_gpt":0.2222697371864975,"score_spread":0.2096782885868804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}