{"id":"W3005750719","doi":"10.1083/jcb.201906147","title":"CDK1 couples proliferation with protein synthesis","year":2020,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Weill Cornell Medical College; RIKEN; Imperial College London; Danmarks Frie Forskningsfond; Lundbeckfonden; Hebrew University of Jerusalem; University of Oxford; University of Ottawa; McGill University; Deutsche Forschungsgemeinschaft; Deutsches Krebsforschungszentrum","keywords":"Cyclin-dependent kinase 1; Protein biosynthesis; Translation (biology); Cell biology; Eukaryotic translation; Cell cycle; Phosphorylation; Cell growth; EIF4E; Biology; Kinase; Messenger RNA; Chemistry; Cell; Molecular biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000196363,0.000554232,0.0003502486,0.000430064,0.000363757,0.0007342359,0.0002559993,0.0002482852,0.002216108],"category_scores_gemma":[0.0003034657,0.0002175121,0.000225033,0.0002490743,0.0002982953,0.0004381573,0.0006598469,0.0005362613,0.001078279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008206884,"about_ca_system_score_gemma":0.0005114785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008030782,"about_ca_topic_score_gemma":0.001462397,"domain_scores_codex":[0.9997857,0.00002062497,0.00001072089,0.00007930926,0.00003489639,0.00006870947],"domain_scores_gemma":[0.9998709,0.00002522717,0.00002721724,0.00001645389,0.00002277882,0.0000375169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002043687,0.00003429228,0.001564453,0.0002309984,0.00001293416,0.0001305702,0.00003019462,0.0005230192,0.9740124,0.002350493,0.0007633013,0.02014296],"study_design_scores_gemma":[0.00002268508,0.000137752,0.009110911,0.00002199854,0.0000214543,0.000368384,0.00004471955,0.002299218,0.9645037,0.001080963,0.02237197,0.00001625823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9069415,0.03866626,0.02044617,0.001370635,0.000582888,0.0001185249,0.001944512,0.0009796523,0.02894983],"genre_scores_gemma":[0.9814093,0.006531736,0.003435203,0.0001890998,0.00009466217,0.0000364084,0.0007311156,0.00009040199,0.007482094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002216108,"threshold_uncertainty_score":0.007413566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259144859961713,"score_gpt":0.2222697371864975,"score_spread":0.2096782885868804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}