{"id":"W3005837422","doi":"10.1101/2020.02.11.944470","title":"A Casz1 - NuRD complex regulates temporal identity transitions in neural progenitors","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Neurogenesis; Gliogenesis; Biology; Neural stem cell; Transcription factor; Cell biology; Nucleosome; Progenitor; Repressor; Progenitor cell; Neuroscience; Histone; Genetics; Stem cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001322594,0.0002450249,0.000202925,0.0003319055,0.0002869145,0.0005757866,0.0002374982,0.0002055036,0.001380406],"category_scores_gemma":[0.0001598118,0.0002410714,0.0001389559,0.0001113298,0.0002307862,0.0001580932,0.000384612,0.0002746033,0.0006616609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007083427,"about_ca_system_score_gemma":0.0002636256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001195085,"about_ca_topic_score_gemma":0.001955927,"domain_scores_codex":[0.9998939,0.000007157796,0.000005649822,0.00002908464,0.00003904598,0.00002513048],"domain_scores_gemma":[0.9999219,0.000009571243,0.00002085021,0.000008675626,0.00001061503,0.00002832144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006517883,0.000008374129,0.0006546534,0.00001852618,0.000004220252,0.00008363247,0.00001177153,0.0001102851,0.9975164,0.0003445215,0.00008155136,0.001101012],"study_design_scores_gemma":[0.0000206822,0.00003853907,0.01972695,0.000006420765,0.000008848707,0.0002548231,0.00003817859,0.003816007,0.9726365,0.0002235433,0.003224071,0.00000548994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873627,0.002190232,0.006348053,0.0001359725,0.00003561105,0.0000145986,0.0003993597,0.0002171275,0.00329628],"genre_scores_gemma":[0.9907783,0.0003870646,0.002285089,0.00002968621,0.000006275356,0.000009547399,0.0005612134,0.00005185109,0.00589102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001380406,"threshold_uncertainty_score":0.00513941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01901273113157154,"score_gpt":0.2410680642461699,"score_spread":0.2220553331145984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}