{"id":"W3005886973","doi":"10.1002/bies.201900232","title":"What Doesn't Kill You Makes You Stronger: Transposons as Dual Players in Chromatin Regulation and Genomic Variation","year":2020,"lang":"en","type":"article","venue":"BioEssays","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Transposable element; Chromatin; Genome; Function (biology); Genetics; Regulation of gene expression; Gene; Genome instability; Mobile genetic elements; Regulator; Chromatin remodeling; Evolutionary biology; Computational biology; DNA; DNA damage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009703632,0.0001288906,0.0001393369,0.00001304292,0.0001257404,0.0001346772,0.00008813538,0.0001070868,0.00057492],"category_scores_gemma":[0.00002503842,0.00006121386,0.00004335575,0.00022933,0.00003949041,0.0002663311,0.00002806885,0.00007310863,0.00004121938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000025227,"about_ca_system_score_gemma":0.00001235827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002352901,"about_ca_topic_score_gemma":0.0007778458,"domain_scores_codex":[0.9990771,0.00006047059,0.000222142,0.0003122337,0.0001423788,0.0001856591],"domain_scores_gemma":[0.9996986,0.00006110706,0.00007066858,0.00004027129,0.00002385394,0.000105462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004783818,0.00006782832,0.009209948,0.00001300975,0.00001595722,0.00000483121,0.002568501,0.0001326656,0.9658852,0.002004172,0.00009143128,0.01995857],"study_design_scores_gemma":[0.0004337727,0.0002695483,0.9880942,0.00002729052,0.00002294921,0.000006870382,0.001190646,0.001732651,0.002799228,0.001444765,0.003752019,0.0002261145],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834031,0.0002364604,0.0000166002,0.01552556,0.0001430673,0.0002404969,0.00007488907,0.00005070784,0.0003090578],"genre_scores_gemma":[0.9987428,0.0001430863,0.0001890873,0.0003231793,0.0002757363,0.00001511193,0.0001620236,0.000001496864,0.0001475289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9788842,"threshold_uncertainty_score":0.6294971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01798109459454656,"score_gpt":0.2085377493144649,"score_spread":0.1905566547199183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}