{"id":"W3005886973","doi":"10.1002/bies.201900232","title":"What Doesn't Kill You Makes You Stronger: Transposons as Dual Players in Chromatin Regulation and Genomic Variation","year":2020,"lang":"en","type":"article","venue":"BioEssays","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Transposable element; Chromatin; Genome; Function (biology); Genetics; Regulation of gene expression; Gene; Genome instability; Mobile genetic elements; Regulator; Chromatin remodeling; Evolutionary biology; Computational biology; DNA; DNA damage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007441587,0.0002424584,0.0004039961,0.0005129136,0.000524928,0.002108753,0.0003590091,0.001074794,0.0009749221],"category_scores_gemma":[0.0004277868,0.0001318291,0.0001881929,0.0004933014,0.002480432,0.001789838,0.001012316,0.00108448,0.0002967471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005313673,"about_ca_system_score_gemma":0.0003889496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000299294,"about_ca_topic_score_gemma":0.0006470843,"domain_scores_codex":[0.9995067,0.0001597387,0.00001873818,0.0001157474,0.0001203013,0.00007870651],"domain_scores_gemma":[0.999749,0.00007074787,0.00006087986,0.00001657088,0.00002968298,0.00007315254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0006351674,0.00008162484,0.01146834,0.00149904,0.0002178151,0.005097122,0.005469509,0.001027039,0.4369097,0.2408578,0.007585309,0.2891515],"study_design_scores_gemma":[0.00005736417,0.0009280284,0.04092345,0.0008550487,0.0002780718,0.01702118,0.008616352,0.002702785,0.09698951,0.3056702,0.5256905,0.0002675861],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2655364,0.627551,0.04119413,0.03633704,0.002025443,0.00004467964,0.0002150296,0.0001783156,0.02691792],"genre_scores_gemma":[0.8119022,0.1493502,0.01408908,0.006012945,0.001904599,0.00003181162,0.0001377848,0.00006335939,0.01650793],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002108753,"threshold_uncertainty_score":0.003935575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01798109459454656,"score_gpt":0.2085377493144649,"score_spread":0.1905566547199183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}