{"id":"W3006172450","doi":"10.1136/bmjqs-2019-010588","title":"REMS in pregnancy: system perfectly designed to the get the results it gets","year":2020,"lang":"en","type":"letter","venue":"BMJ Quality & Safety","topic":"Pregnancy and Medication Impact","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Thalidomide; Isotretinoin; Certification; Patient safety; Pregnancy; Drug; Family medicine; Health care; Medical emergency; Intensive care medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004988684,0.000546545,0.001133723,0.0001199909,0.0002978532,0.00005453829,0.0009363684,0.0006950421,0.00005095914],"category_scores_gemma":[0.006146162,0.0002988545,0.00037861,0.0005008999,0.0001798994,0.00007922912,0.0002026612,0.002763883,0.0005211763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005796594,"about_ca_system_score_gemma":0.001442198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005893551,"about_ca_topic_score_gemma":0.0002305663,"domain_scores_codex":[0.9918122,0.002684905,0.002376742,0.0009244032,0.001423543,0.0007782043],"domain_scores_gemma":[0.9942222,0.0022042,0.0007461507,0.002349849,0.000187303,0.0002903047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001072499,0.00003907613,0.00007046905,0.00170764,0.0001474819,0.0006955541,0.008232879,0.000006858115,0.00004964707,0.00008230138,0.9824591,0.005436451],"study_design_scores_gemma":[0.002481812,0.000236689,0.006024289,0.0148928,0.0002355622,0.0001292605,0.001414382,0.00005773452,0.00007205397,0.0000319005,0.9739773,0.0004461649],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00008778032,0.002758919,0.0009676025,0.9753444,0.0009123121,0.005998575,0.0004652228,0.0002055654,0.01325967],"genre_scores_gemma":[0.05009144,0.0007206827,0.0002034271,0.9342103,0.005584184,0.0008619938,0.0009731315,0.0001061548,0.007248692],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05000366,"threshold_uncertainty_score":0.9999464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08265523782611292,"score_gpt":0.3719259913432974,"score_spread":0.2892707535171845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}