{"id":"W3006182545","doi":"10.1080/15476286.2020.1730081","title":"Transfection of hard-to-transfect primary human macrophages with<i>Bax</i>siRNA to reverse Resveratrol-induced apoptosis","year":2020,"lang":"en","type":"article","venue":"RNA Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Transfection; Resveratrol; Biology; Apoptosis; Small interfering RNA; Cell biology; RNA interference; Molecular biology; Cell culture; Gene; RNA; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119545,0.000224399,0.0003318586,0.00007716448,0.00007441547,0.00001137394,0.0002648537,0.0002112543,0.00004828537],"category_scores_gemma":[0.0000277301,0.0001958006,0.0001400963,0.0002071938,0.00005545457,0.000005562376,0.00005488766,0.0001255945,0.00004311906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000016227,"about_ca_system_score_gemma":0.00005450361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001432276,"about_ca_topic_score_gemma":0.00007366413,"domain_scores_codex":[0.9986371,0.000116763,0.0002860833,0.000561312,0.00008766866,0.0003110742],"domain_scores_gemma":[0.9993346,0.00001018938,0.00005250711,0.0002975854,0.0001154275,0.0001897066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007989253,0.00004343576,0.000856738,0.00003932776,0.0001258511,0.000002855113,0.0001579917,0.00004469376,0.9928765,0.00002350647,0.002824068,0.002206119],"study_design_scores_gemma":[0.0006567113,0.006249849,0.002036749,0.00002320277,0.00004672539,0.000005733704,0.00004238456,0.00000205116,0.9835525,0.00001048833,0.007131951,0.0002416714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936926,0.0001166146,0.003462348,0.001472351,0.0001342047,0.0003563699,0.00006841919,0.00002403064,0.0006730291],"genre_scores_gemma":[0.9941424,0.00009062126,0.0007206955,0.004468894,0.0002741638,0.00003789891,0.0001113835,0.00002730076,0.0001266764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009324007,"threshold_uncertainty_score":0.7984516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02161699926489498,"score_gpt":0.2585530028565028,"score_spread":0.2369360035916079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}