{"id":"W3006301344","doi":"10.1101/gr.254391.119","title":"TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance","year":2020,"lang":"en","type":"article","venue":"Genome Research","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Quadram Institute Bioscience; Medical Research Council Canada","keywords":"Biology; Triclosan; Transposable element; Gene; Genome; Genetics; Computational biology; Bacterial genome size; Mode of action; Mutant; Phenotype; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047374,0.0008314597,0.0007202564,0.0006973403,0.0003317062,0.0008626098,0.0007620084,0.0008023588,0.001469611],"category_scores_gemma":[0.0002902032,0.0004195741,0.0006920815,0.0005269345,0.0005313354,0.0005376959,0.0005606653,0.001453224,0.001091077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000491422,"about_ca_system_score_gemma":0.0003542588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00060134,"about_ca_topic_score_gemma":0.001210586,"domain_scores_codex":[0.9993778,0.00006830128,0.00007436312,0.0001512506,0.0002428227,0.00008544096],"domain_scores_gemma":[0.9996126,0.0001004584,0.0001174671,0.00006394249,0.00005054835,0.00005492258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002527889,0.0000120726,0.0001878547,0.00004156475,0.000004114926,0.00001627848,0.000008485449,0.00003622207,0.9987827,0.00005335371,0.00006620867,0.0007658486],"study_design_scores_gemma":[0.000004267582,0.00006160735,0.003205385,0.00000506887,0.0000124226,0.00014998,0.00002227342,0.0007655301,0.9933453,0.00006083001,0.002360834,0.000006506088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8625452,0.003164299,0.112564,0.0008015581,0.0001900851,0.0002226986,0.01239272,0.00314643,0.004972964],"genre_scores_gemma":[0.8760433,0.002916654,0.0891937,0.0005191995,0.0000405107,0.0002934611,0.01753855,0.0007367872,0.0127179],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001469611,"threshold_uncertainty_score":0.00491637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06246273219159994,"score_gpt":0.3362038884049963,"score_spread":0.2737411562133964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}