{"id":"W3006359148","doi":"10.1039/d0ay00026d","title":"From the beaker to the body: translational challenges for electrochemical, aptamer-based sensors","year":2020,"lang":"en","type":"article","venue":"Analytical Methods","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Oak Ridge Associated Universities","keywords":"Aptamer; Electrochemistry; Nanotechnology; Electrochemical gas sensor; Chemistry; Materials science; Biology; Electrode; Molecular biology; Physical chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007167969,0.0007068467,0.001478373,0.0004985345,0.000707952,0.005263271,0.001692023,0.003538394,0.004343151],"category_scores_gemma":[0.00530272,0.0005076061,0.0004906637,0.0005927744,0.002934552,0.008241155,0.001628545,0.00505098,0.002404303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001332636,"about_ca_system_score_gemma":0.00257719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001345545,"about_ca_topic_score_gemma":0.002076332,"domain_scores_codex":[0.9985927,0.0004426657,0.00008686933,0.0002394179,0.0004765672,0.00016185],"domain_scores_gemma":[0.9966343,0.001652347,0.0001847884,0.0001812401,0.001031191,0.0003162666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007768495,0.0006573884,0.0009169601,0.006525137,0.00009407085,0.0004827747,0.001726647,0.001596,0.3145177,0.0859636,0.04381175,0.5429311],"study_design_scores_gemma":[0.0001288859,0.002507891,0.002117065,0.00230312,0.0001596868,0.001638883,0.00531743,0.009361824,0.1929578,0.101793,0.6815181,0.0001964038],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0238043,0.7302925,0.0891725,0.1409158,0.005842036,0.000179362,0.0003564036,0.0003979217,0.009039153],"genre_scores_gemma":[0.1840518,0.7001342,0.06942882,0.02760417,0.005853799,0.0005102281,0.0004610569,0.0002178451,0.01173823],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007167969,"threshold_uncertainty_score":0.03790826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05138695240432863,"score_gpt":0.3843505707494647,"score_spread":0.3329636183451361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}