{"id":"W3006397179","doi":"10.1097/01.hs9.0000559920.12010.ca","title":"PF427 FOSTAMATINIB, A SPLEEN TYROSINE KINASE INHIBITOR, FOR THE TREATMENT OF WARM ANTIBODY AUTOIMMUNE HEMOLYTIC ANEMIA: INITIAL RESULTS OF THE OPEN‐LABEL EXTENSION PERIOD OF THE SOAR PHASE 2 STUDY","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Blood groups and transfusion","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Autoimmune hemolytic anemia; Syk; Clinical endpoint; Anemia; Internal medicine; Gastroenterology; Antibody; Immunology; Tyrosine kinase; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002810916,0.001316316,0.001853473,0.0003074932,0.0003032783,0.0008310082,0.0005323805,0.001032853,0.002464005],"category_scores_gemma":[0.001409392,0.0002850591,0.001500717,0.0002864824,0.0005540834,0.0008424337,0.0003032852,0.002154667,0.0006298568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006675409,"about_ca_system_score_gemma":0.00108057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005507371,"about_ca_topic_score_gemma":0.001697267,"domain_scores_codex":[0.9992951,0.0003299956,0.00004319536,0.00008621257,0.0001147132,0.0001306511],"domain_scores_gemma":[0.9990927,0.0002026396,0.0001768329,0.00007190102,0.000127295,0.0003285873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5671114,0.0466322,0.009986501,0.002340076,0.003363675,0.00104685,0.0008075707,0.004163888,0.0782096,0.0005063029,0.01169145,0.2741405],"study_design_scores_gemma":[0.4760414,0.4742517,0.02860733,0.0001241722,0.001075921,0.001373804,0.0001190046,0.001871533,0.007509063,0.0003578522,0.008600276,0.00006776941],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888014,0.005083119,0.0007737876,0.0006695297,0.0001022956,0.001323203,0.001457204,0.00008093359,0.001708629],"genre_scores_gemma":[0.9866073,0.003423853,0.001892522,0.00109043,0.0001977816,0.001496791,0.00333096,0.0000385482,0.001921719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002810916,"threshold_uncertainty_score":0.0148657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03961826487134432,"score_gpt":0.3492578135471121,"score_spread":0.3096395486757678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}