{"id":"W3006397179","doi":"10.1097/01.hs9.0000559920.12010.ca","title":"PF427 FOSTAMATINIB, A SPLEEN TYROSINE KINASE INHIBITOR, FOR THE TREATMENT OF WARM ANTIBODY AUTOIMMUNE HEMOLYTIC ANEMIA: INITIAL RESULTS OF THE OPEN‐LABEL EXTENSION PERIOD OF THE SOAR PHASE 2 STUDY","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Blood groups and transfusion","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Autoimmune hemolytic anemia; Syk; Clinical endpoint; Anemia; Internal medicine; Gastroenterology; Antibody; Immunology; Tyrosine kinase; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003897585,0.0002584177,0.000713902,0.00002411099,0.0001756357,0.00001503099,0.0003677435,0.0001161349,0.00009227473],"category_scores_gemma":[0.00009160686,0.0001143338,0.0002447851,0.0003307171,0.0001788808,0.0000683973,0.0001610299,0.0001609463,0.00000200443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004233231,"about_ca_system_score_gemma":0.0002056445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005660806,"about_ca_topic_score_gemma":0.00008465638,"domain_scores_codex":[0.99808,0.0001020281,0.0007896984,0.0003460566,0.0004462397,0.0002359826],"domain_scores_gemma":[0.9977053,0.0002273108,0.0004229249,0.001327421,0.0002690389,0.00004802101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01665924,0.03750163,0.008838592,0.001136795,0.00061811,0.00003568662,0.01504492,0.00003185888,0.8852962,0.0002152621,0.0007796653,0.03384203],"study_design_scores_gemma":[0.1771972,0.03070157,0.04176675,0.002385801,0.002812685,0.00008931569,0.01070625,0.001919502,0.7286649,0.00008302307,0.003301174,0.0003718305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895846,0.001626362,0.00001982699,0.001412968,0.0003838184,0.006365482,0.0001938319,0.00001332917,0.0003997944],"genre_scores_gemma":[0.9986045,0.0000825234,0.0002262508,0.00006968078,0.00008003601,0.00006430959,0.0000328845,0.00003728638,0.0008025501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.160538,"threshold_uncertainty_score":0.4662397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03961826487134432,"score_gpt":0.3492578135471121,"score_spread":0.3096395486757678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}