{"id":"W3006430067","doi":"10.1002/vjch.201900094","title":"Modification of the vinylogous aldol condensation – Another approach to the synthesis of C(15)‐alkylidene and benzylidene andrographolide derivatives","year":2019,"lang":"en","type":"article","venue":"Vietnam Journal of Chemistry","topic":"Andrographolide Research and Applications","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Natural Science Foundation of China","keywords":"Aldol reaction; Aldol condensation; Chemistry; Andrographolide; Benzaldehyde; Pyrrolidine; Catalysis; Moiety; Organic chemistry; Butenolide; Knoevenagel condensation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001341858,0.0003731976,0.0002443726,0.0002568805,0.0001387917,0.0001980665,0.0002785367,0.0001984484,0.001154822],"category_scores_gemma":[0.0001203127,0.0001357624,0.0002765568,0.0001973707,0.0002049913,0.0002190835,0.000243209,0.0004625209,0.0005369958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001856255,"about_ca_system_score_gemma":0.0003184595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004696413,"about_ca_topic_score_gemma":0.001460856,"domain_scores_codex":[0.9998586,0.00002721631,0.00001267896,0.00002768801,0.0000374487,0.00003638053],"domain_scores_gemma":[0.9999367,0.000009294527,0.00001633311,0.00001137345,0.00001102614,0.00001532081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003591195,0.00002539312,0.00008935206,0.00008422091,0.00001979203,0.0001453824,0.00004563501,0.0001780113,0.9940539,0.0004413226,0.00006246893,0.004818726],"study_design_scores_gemma":[0.00001058257,0.0001835252,0.0006569704,0.000003623023,0.00001587608,0.0002662248,0.00001734756,0.000208171,0.9907867,0.0000875717,0.007751501,0.00001185633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8904982,0.007389427,0.08369114,0.0003488493,0.0002972052,0.0004159981,0.000682392,0.000351703,0.01632508],"genre_scores_gemma":[0.9680253,0.002997091,0.02029552,0.00006979834,0.00002486696,0.00006532655,0.0003080026,0.00004360436,0.008170462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154822,"threshold_uncertainty_score":0.003863215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791065477504785,"score_gpt":0.2713563081900215,"score_spread":0.2534456534149737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}