{"id":"W3006430067","doi":"10.1002/vjch.201900094","title":"Modification of the vinylogous aldol condensation – Another approach to the synthesis of C(15)‐alkylidene and benzylidene andrographolide derivatives","year":2019,"lang":"en","type":"article","venue":"Vietnam Journal of Chemistry","topic":"Andrographolide Research and Applications","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Natural Science Foundation of China","keywords":"Aldol reaction; Aldol condensation; Chemistry; Andrographolide; Benzaldehyde; Pyrrolidine; Catalysis; Moiety; Organic chemistry; Butenolide; Knoevenagel condensation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004713112,0.0001052086,0.0003068133,0.00006815399,0.00005761798,0.00001375646,0.0002376901,0.00007257182,0.00004463403],"category_scores_gemma":[0.0002422807,0.00005962757,0.0001695246,0.0003973107,0.0001906489,0.00005874509,0.00004326683,0.0001969023,0.000001232874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001820257,"about_ca_system_score_gemma":0.00009762435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008313138,"about_ca_topic_score_gemma":4.587135e-7,"domain_scores_codex":[0.9988366,0.00004838358,0.0004387409,0.0001291286,0.0004103903,0.0001366953],"domain_scores_gemma":[0.9985645,0.0001474833,0.0004651684,0.0003709468,0.0003599052,0.00009197078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001677738,0.0002071107,0.018349,0.0002818653,0.0001617054,5.254174e-7,0.0003291072,0.0001034856,0.9764689,0.00007453674,0.0003640605,0.003491875],"study_design_scores_gemma":[0.0006174236,0.00008641369,0.04467172,0.0002537406,0.0001258662,0.0001930331,0.001369824,0.0001434265,0.9516196,0.0001603373,0.0006855648,0.00007307118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994024,0.001021847,0.0008637417,0.001597543,0.00001362874,0.0003714885,0.00001384829,0.000003760468,0.00209015],"genre_scores_gemma":[0.9985278,0.0002543886,0.0008894327,0.00008104071,0.00005276917,0.00002002485,0.000002171236,0.00001265804,0.0001597753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02632271,"threshold_uncertainty_score":0.2431542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791065477504785,"score_gpt":0.2713563081900215,"score_spread":0.2534456534149737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}