{"id":"W3006443337","doi":"10.7150/jca.36919","title":"Sensitization of Carboplatinum- and Taxol-Resistant High-Grade Serous Ovarian Cancer Cells Carrying p53, BRCA1/2 Mutations by Emblica officinalis (Amla) via Multiple Targets","year":2020,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Cancer research; Ovarian cancer; Angiogenesis; Epidermal growth factor receptor; Serous fluid; Cancer; PI3K/AKT/mTOR pathway; Biology; Chemistry; Pathology; Medicine; Internal medicine; Cell biology; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000882844,0.0001911225,0.0001612746,0.0001832474,0.0001010074,0.0001152911,0.0001089901,0.0001252232,0.001031523],"category_scores_gemma":[0.00004749363,0.00006179293,0.0002004602,0.0001499473,0.00009336683,0.00009436088,0.00009182894,0.0002564704,0.0001380381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001246493,"about_ca_system_score_gemma":0.0001087735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004937607,"about_ca_topic_score_gemma":0.0007312664,"domain_scores_codex":[0.9999471,0.000009771795,0.000006863957,0.000009861951,0.00001259247,0.00001379172],"domain_scores_gemma":[0.999966,0.000006987877,0.000009093533,0.000006714627,0.000004264232,0.000006915191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002276168,0.0001209678,0.0003280978,0.00005005245,0.000005906831,0.00003465825,0.00001812684,0.00007481878,0.997399,0.00003688937,0.00003759628,0.001666276],"study_design_scores_gemma":[0.00006306417,0.001389768,0.007436968,0.000005406893,0.00002376731,0.0002459063,0.0000259302,0.000590019,0.9887045,0.00001895499,0.001492676,0.000003050967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980558,0.0007242644,0.0003740769,0.00002391318,0.00000840692,0.00002719967,0.0001578782,0.000022211,0.0006061451],"genre_scores_gemma":[0.9976253,0.0005691937,0.0005035506,0.00001856485,0.000003554597,0.00002632204,0.0003247566,0.000003322313,0.0009255068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031523,"threshold_uncertainty_score":0.003450751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008401015400052446,"score_gpt":0.2356045352525367,"score_spread":0.2272035198524843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}