{"id":"W3006443337","doi":"10.7150/jca.36919","title":"Sensitization of Carboplatinum- and Taxol-Resistant High-Grade Serous Ovarian Cancer Cells Carrying p53, BRCA1/2 Mutations by Emblica officinalis (Amla) via Multiple Targets","year":2020,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Cancer research; Ovarian cancer; Angiogenesis; Epidermal growth factor receptor; Serous fluid; Cancer; PI3K/AKT/mTOR pathway; Biology; Chemistry; Pathology; Medicine; Internal medicine; Cell biology; Signal transduction","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008508558,0.0001303278,0.000233982,0.00004333789,0.00007268425,0.00001900397,0.00006637836,0.0001164047,0.00003818158],"category_scores_gemma":[0.00002798856,0.0001161483,0.00007595504,0.0001181751,0.00003689053,0.00001159821,0.00002758579,0.00009478689,1.831544e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003464573,"about_ca_system_score_gemma":0.0001178532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006959084,"about_ca_topic_score_gemma":0.0003950518,"domain_scores_codex":[0.9990592,0.0000483732,0.0003797142,0.0001730105,0.0002011297,0.0001385967],"domain_scores_gemma":[0.9990321,0.00001724221,0.0004693257,0.00008632107,0.0002729613,0.0001220322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001621635,0.00002418198,0.0006859316,0.00005641283,0.0001129673,0.000006704468,0.0002600643,0.009041457,0.9861202,0.00001370359,0.001016878,0.00249932],"study_design_scores_gemma":[0.001365497,0.0002615165,0.004127034,0.00006025101,0.0001541552,0.00001301457,0.00009861033,0.005848253,0.9818641,0.00003984514,0.00599202,0.0001757358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776202,0.006163389,0.01397032,0.001619723,0.0002789494,0.000158849,0.000162619,0.000004152964,0.00002178459],"genre_scores_gemma":[0.9967473,0.00120812,0.001291069,0.0002147384,0.0003836452,0.000004446158,0.00005043164,0.00002241975,0.00007786448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01912705,"threshold_uncertainty_score":0.4736391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008401015400052446,"score_gpt":0.2356045352525367,"score_spread":0.2272035198524843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}