{"id":"W3006494848","doi":"10.1093/jnen/nlaa005","title":"Immunohistochemical and nanoString-Based Subgrouping of Clinical Medulloblastoma Samples","year":2020,"lang":"en","type":"article","venue":"Journal of Neuropathology & Experimental Neurology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Ontario Genomics Institute; Genome Canada","keywords":"Medulloblastoma; Immunohistochemistry; Wnt signaling pathway; Sonic hedgehog; Medicine; Pathology; Oncology; Internal medicine; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002849588,0.0001920019,0.0009286465,0.0001235678,0.00003727768,0.000004755835,0.0001304928,0.0001592827,0.00003045205],"category_scores_gemma":[0.000512811,0.0001590358,0.000296,0.0001058256,0.0004603799,0.00004439524,0.0001006104,0.0004896651,0.000002873698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000116225,"about_ca_system_score_gemma":0.00007856151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002587875,"about_ca_topic_score_gemma":2.401297e-7,"domain_scores_codex":[0.9978176,0.0002799088,0.001167719,0.0003021068,0.0001964019,0.0002362676],"domain_scores_gemma":[0.9982663,0.0004906387,0.0006785789,0.0001607783,0.00009605326,0.0003076621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004067903,0.0008078037,0.1807998,0.00001950357,0.00005005365,0.005839935,0.0001216735,0.00000492611,0.8075832,0.00003013223,0.000123379,0.0005517507],"study_design_scores_gemma":[0.007557543,0.02262257,0.3240019,0.00003201136,0.000167128,0.009840108,0.00007025233,0.00009712589,0.6346163,0.000007719678,0.000871252,0.0001160676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930604,0.00182292,0.00004325093,0.00446087,0.0004038175,0.0001528437,0.000003905812,0.00001451072,0.00003754843],"genre_scores_gemma":[0.9937993,0.00006918825,0.0007965881,0.00510335,0.000199446,0.000002853465,0.000002183124,0.00002647385,5.608218e-7],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1729668,"threshold_uncertainty_score":0.6485294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05458480858892154,"score_gpt":0.3452548827314954,"score_spread":0.2906700741425738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}