{"id":"W3006494848","doi":"10.1093/jnen/nlaa005","title":"Immunohistochemical and nanoString-Based Subgrouping of Clinical Medulloblastoma Samples","year":2020,"lang":"en","type":"article","venue":"Journal of Neuropathology & Experimental Neurology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Ontario Genomics Institute; Genome Canada","keywords":"Medulloblastoma; Immunohistochemistry; Wnt signaling pathway; Sonic hedgehog; Medicine; Pathology; Oncology; Internal medicine; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001557674,0.0003084789,0.0003861955,0.00252477,0.0002687195,0.0003276224,0.0002966042,0.0003455794,0.001178616],"category_scores_gemma":[0.002064675,0.0001879893,0.0003087025,0.0008321477,0.0004481562,0.000284484,0.0003569742,0.0002082328,0.0004168595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003326338,"about_ca_system_score_gemma":0.0002639959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001192307,"about_ca_topic_score_gemma":0.002056862,"domain_scores_codex":[0.9989742,0.0001848365,0.0002157623,0.0002378455,0.000287557,0.00009977115],"domain_scores_gemma":[0.9989747,0.0003056145,0.0001683604,0.0002078766,0.000266625,0.0000768584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001815529,0.000152094,0.3637945,0.0003372124,0.0001740477,0.001739759,0.0006550102,0.0007091316,0.604119,0.0002916127,0.000354045,0.025858],"study_design_scores_gemma":[0.000104245,0.00110929,0.6981828,0.00006587095,0.0003761081,0.01020554,0.001120526,0.006382253,0.2752369,0.0005081291,0.006663904,0.00004450022],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876624,0.001076377,0.00834654,0.00003991506,0.00002403867,0.0003399149,0.0007608788,0.00009511851,0.001654812],"genre_scores_gemma":[0.985294,0.0005783018,0.01159049,0.00003343997,0.00001981688,0.0002549769,0.001660922,0.00003166039,0.0005363367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00252477,"threshold_uncertainty_score":0.008237898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05458480858892154,"score_gpt":0.3452548827314954,"score_spread":0.2906700741425738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}