{"id":"W3006593042","doi":"10.3390/ijms21041308","title":"Intratumor Heterogeneity and Therapy Resistance: Contributions of Dormancy, Apoptosis Reversal (Anastasis) and Cell Fusion to Disease Recurrence","year":2020,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Dormancy; Apoptosis; Disease; Cell fusion; Fusion; Cell; Cancer research; Medicine; Biology; Bioinformatics; Oncology; Internal medicine; Genetics; Botany; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005647826,0.0006709081,0.001268094,0.002581704,0.0002678753,0.001184466,0.000741147,0.001258982,0.002627648],"category_scores_gemma":[0.0006226544,0.0002559886,0.0004691189,0.00161019,0.0008236601,0.001343997,0.0006592363,0.001859857,0.001129536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006922761,"about_ca_system_score_gemma":0.0009340958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001016349,"about_ca_topic_score_gemma":0.001691019,"domain_scores_codex":[0.9998235,0.00003469509,0.00002180923,0.00003885428,0.00006313924,0.00001803308],"domain_scores_gemma":[0.9997072,0.0001644473,0.0000397308,0.000008436085,0.00005578319,0.0000244137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007308347,0.00008055375,0.0002880018,0.01479913,0.00007230659,0.0002825736,0.00008351187,0.000433924,0.002260243,0.008854281,0.01607968,0.9566927],"study_design_scores_gemma":[0.00001845275,0.0001638223,0.001763744,0.004219552,0.0001408981,0.003023225,0.0001202777,0.0002119954,0.00125115,0.005540873,0.9835142,0.0000318522],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001127691,0.9988549,0.00009944881,0.0002022985,0.00009989719,0.000002902543,0.00000696432,0.000004550995,0.0006163765],"genre_scores_gemma":[0.0009212705,0.9983046,0.000109736,0.0001417661,0.0001186962,0.000005377859,0.00001280186,0.000001287404,0.0003844637],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002627648,"threshold_uncertainty_score":0.008790314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03065816303849681,"score_gpt":0.3564120336509412,"score_spread":0.3257538706124443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}