{"id":"W3006599309","doi":"10.1002/chem.202000773","title":"Smart Protein‐Based Formulation of Dendritic Mesoporous Silica Nanoparticles: Toward Oral Delivery of Insulin","year":2020,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Lévis","funders":"Universität Wien","keywords":"Insulin; Mesoporous silica; Chemistry; Endocytosis; Permeation; Nanoparticle; Mesoporous material; Nanotechnology; Materials science; Internal medicine; Biochemistry; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007324271,0.0002180721,0.0003685412,0.00003464855,0.0001152754,0.00001476755,0.0003750455,0.00009803777,0.0006224044],"category_scores_gemma":[0.000279024,0.0002173867,0.000171723,0.0002113424,0.0001723521,0.000155562,0.00008208519,0.0007223778,0.0000510731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006070916,"about_ca_system_score_gemma":0.0001696826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001518148,"about_ca_topic_score_gemma":1.756484e-7,"domain_scores_codex":[0.9976463,0.0006082141,0.0009191207,0.0002403021,0.0002632751,0.0003227737],"domain_scores_gemma":[0.9983897,0.0001054881,0.0006303433,0.0001688357,0.0003154674,0.0003902083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007009445,0.0001913229,0.001533616,0.0004306001,0.0001005476,0.0002330435,0.0008217183,0.003214852,0.986138,0.000007717602,0.0003850198,0.006242618],"study_design_scores_gemma":[0.003105947,0.0002501371,0.0003356256,0.0001165579,0.0001210542,0.0001378201,0.000381335,0.02242027,0.9617275,0.00002057047,0.01114895,0.0002342472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996407,0.0007314843,0.001077912,0.0004057796,0.0001345085,0.0002380431,0.00004559293,0.00005044961,0.0009092126],"genre_scores_gemma":[0.9981186,0.00002863777,0.001093085,0.0003699087,0.0002474673,0.000004566125,0.00001458815,0.00004089189,0.00008227026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02441051,"threshold_uncertainty_score":0.8864772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1151498648896934,"score_gpt":0.3544343879676358,"score_spread":0.2392845230779424,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}