{"id":"W3006625121","doi":"10.1080/03007995.2020.1729708","title":"Varenicline: mode of action, efficacy, safety and accumulated experience salient for clinical populations","year":2020,"lang":"en","type":"review","venue":"Current Medical Research and Opinion","topic":"Smoking Behavior and Cessation","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Varenicline; Medicine; Smoking cessation; Nicotine replacement therapy; Adverse effect; Clinical trial; Pharmacology; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001348759,0.0002008516,0.00112388,0.000198079,0.0001572638,0.00002343509,0.0001498584,0.0004448773,0.00007565924],"category_scores_gemma":[0.006177403,0.0001476622,0.0002164575,0.0004103828,0.0004255188,0.00005272938,0.0001691787,0.001126424,0.000001724842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007736923,"about_ca_system_score_gemma":0.0007791676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001669692,"about_ca_topic_score_gemma":0.000001612773,"domain_scores_codex":[0.9965658,0.0003232002,0.001083688,0.0005420496,0.00118311,0.0003022132],"domain_scores_gemma":[0.9970878,0.001351395,0.0002046689,0.0002622539,0.0003327256,0.0007611394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002041413,0.0003156331,0.001294352,0.006319461,0.00003039692,0.000001630906,0.00009440359,3.727015e-8,1.849954e-7,0.0004250409,0.001469682,0.989845],"study_design_scores_gemma":[0.001538966,0.0006246101,0.004050638,0.0136811,0.0001742096,0.0000160406,0.00005199143,0.0004304317,0.000001249488,0.00007287922,0.979225,0.0001329063],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00155067,0.9931962,0.001593962,0.0004511902,0.001254685,0.001802742,0.000103654,0.00003388468,0.00001298256],"genre_scores_gemma":[0.003605247,0.9940851,0.00005561164,0.00001053178,0.0006940428,0.0001123629,0.001401144,0.00002409015,0.0000118955],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9897121,"threshold_uncertainty_score":0.7395375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6961278574739443,"score_gpt":0.6769596484335964,"score_spread":0.01916820904034799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}