{"id":"W3006825747","doi":"10.1128/msphere.00913-19","title":"Metabolic Reprogramming in the Opportunistic Yeast Candida albicans in Response to Hypoxia","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Government of Canada; Fondation CHU de Québec; Centre Hospitalier Universitaire de Québec; Natural Sciences and Engineering Research Council of Canada","keywords":"Lipidome; Metabolome; Candida albicans; Biology; Metabolomics; Ergosterol; Biochemistry; Metabolic pathway; Pentose phosphate pathway; Yeast; Cell biology; Microbiology; Lipidomics; Metabolism; Glycolysis; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000630526,0.0001844447,0.0001916159,0.0002811334,0.0002807177,0.0003952358,0.0001162355,0.0002195986,0.0008162759],"category_scores_gemma":[0.00009405051,0.00006808195,0.0002496287,0.0003351184,0.000121795,0.0001518574,0.0002923532,0.0003572832,0.0001637252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001865572,"about_ca_system_score_gemma":0.0002591726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001610118,"about_ca_topic_score_gemma":0.002001995,"domain_scores_codex":[0.9999098,0.00001045822,0.000005154222,0.00002321105,0.00002761944,0.00002376412],"domain_scores_gemma":[0.9999603,0.000004839336,0.000008598941,0.000004290703,0.00001220532,0.000009858847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001759238,0.00002121855,0.001083759,0.00006032112,0.000007631011,0.0002340231,0.00003940194,0.000224359,0.9938513,0.0001899703,0.0001913708,0.003920821],"study_design_scores_gemma":[0.00002138892,0.000462299,0.08652173,0.00006060539,0.00005965066,0.001300708,0.0007093101,0.004504627,0.8904909,0.001139181,0.01468397,0.00004572816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865324,0.00376087,0.002676033,0.0003230821,0.00009555837,0.00003824644,0.002578892,0.0001102834,0.003884555],"genre_scores_gemma":[0.9912,0.002408745,0.002605872,0.0002565843,0.00001817319,0.00003399093,0.001511667,0.00002570353,0.001939277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001610118,"threshold_uncertainty_score":0.003201485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04365688164241893,"score_gpt":0.3009801725422692,"score_spread":0.2573232908998502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}