{"id":"W3006913961","doi":"10.1093/jcag/gwz047.208","title":"A209 ROLE OF SEROTONIN-AUTOPHAGY AXIS IN REGULATION OF EPITHELIAL CELL FUNCTION AND MICROBIOTA COMPOSITION IN GUT","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; McMaster University; Population Health Research Institute","funders":"","keywords":"Autophagy; Gut flora; Proinflammatory cytokine; Colitis; Dysbiosis; Barrier function; Inflammation; Inflammatory bowel disease; Intestinal epithelium; Intestinal mucosa; Biology; Cell biology; Immunology; Chemistry; Epithelium; Internal medicine; Biochemistry; Medicine; Apoptosis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001191202,0.0001542621,0.0002761076,0.0001843571,0.000155102,0.0002901025,0.00009132507,0.000321515,0.001285428],"category_scores_gemma":[0.00006191986,0.00007607121,0.0002894549,0.000093862,0.0001992813,0.000221409,0.0001598991,0.0003333442,0.0001843539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003228511,"about_ca_system_score_gemma":0.0001947223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006019667,"about_ca_topic_score_gemma":0.0008854179,"domain_scores_codex":[0.9998819,0.00002733785,0.00001043706,0.00002493599,0.00002147785,0.00003384858],"domain_scores_gemma":[0.9999037,0.00000904827,0.00002591721,0.00000661805,0.00001844471,0.00003625308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008214636,0.00004033476,0.002885835,0.0003295245,0.00003882053,0.0001821764,0.00003055594,0.00006640273,0.9914827,0.0002142497,0.0001775459,0.003730437],"study_design_scores_gemma":[0.0001334468,0.002167765,0.2953832,0.0001598582,0.0002119231,0.001421852,0.0004328853,0.00257713,0.6868731,0.0006859912,0.009918193,0.00003473753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700551,0.0249336,0.0016481,0.0003899982,0.00009499143,0.0000253177,0.000670886,0.0000781985,0.002103881],"genre_scores_gemma":[0.9951354,0.002453084,0.0008096401,0.0001247019,0.00001748472,0.00002094756,0.000247,0.000005670836,0.001186196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001285428,"threshold_uncertainty_score":0.004300177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003677510223131985,"score_gpt":0.1883283470937958,"score_spread":0.1846508368706638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}