{"id":"W3006939649","doi":"10.1111/cts.12771","title":"Pharmacogenomics in Asian Subpopulations and Impacts on Commonly Prescribed Medications","year":2020,"lang":"en","type":"review","venue":"Clinical and Translational Science","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Pharmacogenetics; Medicine; Pharmacogenomics; Carbamazepine; Context (archaeology); CYP2C19; Population; Pharmacology; Drug; Internal medicine; Genotype; Genetics; Biology; Psychiatry; Epilepsy; Gene; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001498861,0.0002172818,0.0007502689,0.0006926955,0.0001881491,0.0009205964,0.0002496437,0.000321675,0.002443368],"category_scores_gemma":[0.003696955,0.0001215239,0.001365054,0.001890137,0.0002792559,0.0004516538,0.000424635,0.0007487568,0.0002205853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003736188,"about_ca_system_score_gemma":0.0007737904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004481963,"about_ca_topic_score_gemma":0.004645262,"domain_scores_codex":[0.9991172,0.0003163035,0.0001584164,0.0001556776,0.0001836385,0.00006871711],"domain_scores_gemma":[0.9984503,0.0006849648,0.000465538,0.00009200539,0.000240535,0.00006672038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001139803,0.0001216409,0.4586487,0.008503225,0.008845897,0.002234964,0.001646468,0.001139413,0.003521619,0.005596874,0.008736055,0.4998653],"study_design_scores_gemma":[0.00007969733,0.0003428712,0.8788607,0.003250649,0.008413939,0.005935229,0.001431086,0.0007520497,0.001586726,0.007372724,0.09189592,0.00007838246],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4004015,0.5595934,0.003456862,0.00998932,0.0003993648,0.00009261485,0.006721784,0.00008702666,0.01925795],"genre_scores_gemma":[0.7241047,0.2654878,0.00217875,0.003141026,0.0004692934,0.00006974179,0.002873748,0.00005046375,0.00162443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004481963,"threshold_uncertainty_score":0.008911788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1939635517204557,"score_gpt":0.4925846188705731,"score_spread":0.2986210671501174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}