{"id":"W3007114603","doi":"10.1093/jcag/gwz047.082","title":"A83 INTESTINAL EPITHELIAL CELL STEMNESS AND DIFFERENTIATION ARE REGULATED BY THE HIPPO PATHWAY EFFECTOR YAP1","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"YAP1; LGR5; Hippo signaling pathway; Biology; Stem cell; Cell biology; Wnt signaling pathway; Transcription factor; Cellular differentiation; Cancer stem cell; Cell growth; Cancer research; Molecular biology; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005698584,0.0001849439,0.0001392019,0.0001989939,0.0002043652,0.0002565075,0.00009641478,0.0001716781,0.001778599],"category_scores_gemma":[0.00006451488,0.0001134956,0.0002108712,0.0001130053,0.0001448017,0.0002117066,0.0002401109,0.0003905452,0.0003051592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002418281,"about_ca_system_score_gemma":0.0001772538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007206646,"about_ca_topic_score_gemma":0.0008898629,"domain_scores_codex":[0.9999381,0.000005188834,0.000004568996,0.00001432344,0.00001819796,0.00001956657],"domain_scores_gemma":[0.9999325,0.000003988439,0.00002602062,0.000003302259,0.00001143008,0.0000227933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009672343,0.00001347392,0.0009138006,0.00007814704,0.000007218413,0.00008506039,0.00001822173,0.00006122838,0.996901,0.0001412712,0.0001356632,0.00154818],"study_design_scores_gemma":[0.00004203794,0.0004233899,0.08641506,0.00003848887,0.00005674817,0.0006784787,0.0002780506,0.003898301,0.8969951,0.0001985799,0.01096049,0.00001520492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920679,0.003051856,0.002107353,0.0001730436,0.00002255872,0.00001737566,0.0008061082,0.00009274997,0.001660966],"genre_scores_gemma":[0.9947135,0.00104817,0.0006653949,0.00004794762,0.000006055731,0.00002514266,0.0009611476,0.00001033636,0.002522237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001778599,"threshold_uncertainty_score":0.005950034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009054337715345886,"score_gpt":0.2070750846566059,"score_spread":0.19802074694126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}