{"id":"W3007124108","doi":"10.1101/2020.02.20.956300","title":"GREM1 is epigenetically reprogrammed in muscle cells after exercise training and controls myogenesis and metabolism","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Myogenesis; Epigenome; Skeletal muscle; Biology; Epigenetics; DNA methylation; Cell biology; Stem cell; Endocrinology; Gene expression; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001180697,0.0001625877,0.0001816232,0.0001837909,0.0001046784,0.0001911154,0.0001359167,0.0002404653,0.002470035],"category_scores_gemma":[0.0001303686,0.0001085852,0.0001783051,0.0001436323,0.000186711,0.0001087895,0.0002473725,0.000286115,0.0007877366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001685248,"about_ca_system_score_gemma":0.0001020223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005254057,"about_ca_topic_score_gemma":0.0009723494,"domain_scores_codex":[0.9999324,0.000007584016,0.000003073476,0.00002475388,0.00001788405,0.00001430567],"domain_scores_gemma":[0.9999441,0.000006026529,0.00001931279,0.00001033933,0.000007201456,0.00001313416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009516424,0.000005341959,0.001125199,0.00002469921,0.000004977108,0.00004279757,0.00001605642,0.00004292339,0.9958388,0.0001282583,0.0000929985,0.002582829],"study_design_scores_gemma":[0.0000243278,0.0001362918,0.09858532,0.0000159786,0.00002204179,0.0004223213,0.0000679214,0.001147354,0.8927692,0.0002998119,0.006500995,0.000008364036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829775,0.002798054,0.007859467,0.0003144972,0.0001147333,0.00001636693,0.001395146,0.0003072509,0.004216923],"genre_scores_gemma":[0.9852157,0.0007170456,0.002162814,0.00009817564,0.00002453888,0.00002021296,0.001342141,0.00007251192,0.01034681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002470035,"threshold_uncertainty_score":0.008263111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115043552605335,"score_gpt":0.2128327457793079,"score_spread":0.2013283905187744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}