{"id":"W3007152931","doi":"10.1515/hsz-2019-0427","title":"Proteostasis in thermogenesis and obesity","year":2020,"lang":"en","type":"review","venue":"Biological Chemistry","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Proteostasis; Thermogenesis; Biology; Endoplasmic reticulum; Cell biology; Unfolded protein response; Overnutrition; Autophagy; Adipose tissue; Endocrinology; Obesity; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008649049,0.000270331,0.001409766,0.00001429561,0.0000176026,0.000005421179,0.00009608977,0.0005979371,0.0002790462],"category_scores_gemma":[0.0002029928,0.0001625253,0.0001909116,0.0001402787,0.00006404531,0.000007158347,0.0001081137,0.0003670549,0.00003403561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003362007,"about_ca_system_score_gemma":0.00009983112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005153578,"about_ca_topic_score_gemma":9.641796e-8,"domain_scores_codex":[0.9989885,0.00004203135,0.0002869558,0.0004246137,0.00007240912,0.0001854686],"domain_scores_gemma":[0.9994876,0.00005240863,0.00009005886,0.000184114,0.0000124613,0.0001734047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001247493,0.00005578175,0.0003001542,0.01186647,0.00005224717,0.0002187189,0.000007370587,3.631874e-10,0.0004257733,0.000005809167,0.00004911568,0.9870061],"study_design_scores_gemma":[0.0001659522,0.00002830752,0.0008322353,0.001748534,0.0003204704,0.0001530499,0.000003803116,8.307651e-8,0.0003840431,0.00001061163,0.9961751,0.0001778084],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004260934,0.9941598,8.264689e-7,0.00005030599,0.0000135323,0.0005278899,0.00003571153,0.0000431321,0.0009078481],"genre_scores_gemma":[0.0004454576,0.998445,0.0001384466,0.00006540111,0.0002833569,0.00008998895,0.00008279402,0.00001632317,0.0004332186],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.996126,"threshold_uncertainty_score":0.6627591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09079020822081664,"score_gpt":0.3369704532859286,"score_spread":0.246180245065112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}