{"id":"W3007176524","doi":"10.1016/j.ydbio.2020.02.011","title":"The predicted collagen-binding domains of Drosophila SPARC are essential for survival and for collagen IV distribution and assembly into basement membranes","year":2020,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Research Council Canada","keywords":"Colocalization; Cell biology; Biology; Matricellular protein; Mutant; Imaginal disc; Basement membrane; Intracellular; Phenotype; Extracellular matrix; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009728475,0.000325219,0.0002067495,0.0002701078,0.0002573544,0.0002572923,0.0002103116,0.0002972211,0.001265857],"category_scores_gemma":[0.0001909611,0.0001576908,0.0003028501,0.0001086697,0.0002539798,0.0001586229,0.0001642085,0.0004078543,0.0006005355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003355567,"about_ca_system_score_gemma":0.0002934615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002116035,"about_ca_topic_score_gemma":0.003720491,"domain_scores_codex":[0.9999275,0.000007474137,0.000006555541,0.00001455129,0.00002887609,0.00001508814],"domain_scores_gemma":[0.9997634,0.00003886644,0.00006096354,0.00001760145,0.00004261224,0.00007645679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001627638,0.00001394988,0.001754287,0.00004695332,0.00001398152,0.0003361554,0.00001743823,0.0002848937,0.9950519,0.0003241355,0.0001522424,0.00184124],"study_design_scores_gemma":[0.00003376634,0.0001505648,0.07442564,0.00001517842,0.00004352845,0.002161247,0.00007696894,0.005066959,0.9108077,0.0002132981,0.006984233,0.00002087074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904942,0.001036163,0.005750891,0.00009504109,0.00004054402,0.00002064488,0.0009726473,0.00008433152,0.001505749],"genre_scores_gemma":[0.9917507,0.0002094214,0.004867105,0.0001014261,0.00001132215,0.00001217091,0.001580078,0.00002723262,0.001440428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002116035,"threshold_uncertainty_score":0.004234731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0286117319493216,"score_gpt":0.2859113457249517,"score_spread":0.2572996137756302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}