{"id":"W3007228332","doi":"10.1152/ajpendo.00033.2020","title":"Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"NOD2; NOD1; Inflammation; Insulin resistance; Internal medicine; Endocrinology; Glucose uptake; Chemistry; Biology; Medicine; Insulin; Receptor; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005749289,0.001195302,0.0007257989,0.0009930601,0.0004034404,0.0008030457,0.0007654061,0.00131088,0.004784109],"category_scores_gemma":[0.0003218474,0.000584899,0.0008957168,0.0003912754,0.0009861843,0.0008181112,0.0005788477,0.003099539,0.001652429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006566438,"about_ca_system_score_gemma":0.0006042197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004026101,"about_ca_topic_score_gemma":0.0008794227,"domain_scores_codex":[0.9991708,0.000121902,0.0001020988,0.0002235823,0.0001886855,0.000193001],"domain_scores_gemma":[0.9990766,0.00006656084,0.0003286431,0.0001262598,0.00006237094,0.0003395213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001698254,0.0006499885,0.0002435361,0.0001131837,0.00003385495,0.0001337332,0.00003969904,0.000162089,0.9937317,0.0005038446,0.0002473722,0.002442773],"study_design_scores_gemma":[0.0008946135,0.004014941,0.006942527,0.00006401934,0.0001091384,0.0008020747,0.000139976,0.002145001,0.9728848,0.0004651365,0.01150038,0.00003731211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749374,0.002904983,0.01028781,0.001617449,0.0004319577,0.0003873719,0.003526755,0.0009812367,0.004925048],"genre_scores_gemma":[0.9495642,0.002182827,0.01707748,0.001515374,0.0001660401,0.001308376,0.004287734,0.0005823473,0.02331556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004784109,"threshold_uncertainty_score":0.01600444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00723070711244835,"score_gpt":0.2504374930959557,"score_spread":0.2432067859835073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}