{"id":"W3007282024","doi":"10.1093/jcag/gwz047.031","title":"A32 THE REGULATION OF INTESTINAL SMOOTH MUSCLE CELL PROLIFERATION IN CROHN’S DISEASE – IS NR4A1 A NOVEL TARGET TO TREAT FIBROSTENOSIS?","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Platelet-derived growth factor receptor; Western blot; Cell growth; Muscle hypertrophy; Cancer research; Crohn's disease; Growth factor; Hyperplasia; Platelet-derived growth factor; Biology; Fibrosis; Medicine; Cell biology; Endocrinology; Immunology; Pharmacology; Internal medicine; Receptor; Disease; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004098614,0.00008177803,0.0002001644,0.0001363974,0.00008857737,0.00002723504,0.0002904755,0.00004533528,0.00007268116],"category_scores_gemma":[0.001107156,0.00005798929,0.0001160076,0.0002275916,0.00003785116,0.0001069907,0.00003234519,0.0001971249,0.000002308627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003896454,"about_ca_system_score_gemma":0.000214922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007650484,"about_ca_topic_score_gemma":0.007162104,"domain_scores_codex":[0.9986352,0.0002792129,0.0004659102,0.0001155793,0.0003018478,0.0002022693],"domain_scores_gemma":[0.998585,0.00009108191,0.0008524724,0.00009763522,0.0001698121,0.0002040216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009936941,0.000139846,0.6424528,0.00004362275,0.00001242807,0.000007640604,0.003748945,0.0103263,0.3280723,0.00009033794,0.01387116,0.0002409834],"study_design_scores_gemma":[0.001312201,0.0006291284,0.9765497,0.00007000218,0.00003985907,0.000005434253,0.0001130322,0.003890655,0.01561391,0.0001473586,0.001564104,0.00006463655],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.943916,0.000003168874,0.0001851753,0.05545464,0.0001454921,0.0001891408,0.00005141067,0.00000191459,0.00005302857],"genre_scores_gemma":[0.9923703,0.000001946182,0.0002047444,0.007250989,0.00008560572,0.000001842217,8.296317e-7,0.000009769417,0.00007397786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3340969,"threshold_uncertainty_score":0.3996622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01705441294275182,"score_gpt":0.2158020356869481,"score_spread":0.1987476227441962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}