{"id":"W3007329046","doi":"10.1002/jia2.25420","title":"Changes in kidney function among men having sex with men starting on demand tenofovir disoproxil fumarate – emtricitabine for HIV pre‐exposure prophylaxis","year":2020,"lang":"en","type":"article","venue":"Journal of the International AIDS Society","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Agence Nationale de la Recherche; Sidaction; Styrelsen för Internationellt Utvecklingssamarbete; Gilead Sciences; CHIST-ERA; Bill and Melinda Gates Foundation","keywords":"Medicine; Emtricitabine; Pre-exposure prophylaxis; Renal function; Tenofovir; Placebo; Urology; Internal medicine; Human immunodeficiency virus (HIV); Antiretroviral therapy; Viral load; Men who have sex with men; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001117416,0.0003152791,0.0005912725,0.0003714106,0.0002019072,0.0004394333,0.0002431559,0.0004049122,0.001293445],"category_scores_gemma":[0.002228531,0.000299875,0.0008721153,0.0003638207,0.0001508069,0.0003860088,0.0002370919,0.0003744239,0.00008306964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002726371,"about_ca_system_score_gemma":0.0002558393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001489149,"about_ca_topic_score_gemma":0.002086456,"domain_scores_codex":[0.9993982,0.0002573219,0.00004995453,0.0001118278,0.0001183464,0.00006436717],"domain_scores_gemma":[0.9990253,0.0002807602,0.0004544511,0.000062246,0.00005564359,0.0001215938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01336805,0.0007989175,0.9718099,0.0001150966,0.0006671622,0.00005720307,0.0001485421,0.0001970244,0.001880107,0.00002516123,0.0001506415,0.01078222],"study_design_scores_gemma":[0.0003940496,0.003786834,0.9940156,0.00001632729,0.0003490822,0.00008513372,0.00005016331,0.0006071182,0.0004752931,0.00002192827,0.0001910776,0.000007480654],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993501,0.0002864561,0.00004901424,0.00001255669,0.000003952411,0.00001833592,0.000167081,0.000002211946,0.0001103511],"genre_scores_gemma":[0.9995692,0.0000643094,0.00006757479,0.00001651254,0.000007342329,0.00001788277,0.0001496387,6.059819e-7,0.000106877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001489149,"threshold_uncertainty_score":0.005909562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01132352402340894,"score_gpt":0.2331775072616923,"score_spread":0.2218539832382833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}