{"id":"W3007378450","doi":"10.1093/jcag/gwz047.052","title":"A53 SACCHAROMYCES BOULARDII CNCM I-745 IMPROVES ANXIETY-LIKE BEHAVIOR AND RESCUES DYSMOTILITY IN A HUMANIZED MOUSE MODEL OF IRRITABLE BOWEL SYNDROME WITH CO-MORBID ANXIETY","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Irritable bowel syndrome; Saccharomyces boulardii; Probiotic; Medicine; Abdominal pain; Anxiety; Gastroenterology; Internal medicine; Gut flora; Immunology; Biology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002063906,0.000846679,0.0006897516,0.0008264706,0.0002008379,0.0003038699,0.0004002634,0.0006640665,0.00164152],"category_scores_gemma":[0.0001049534,0.0002720151,0.0006196284,0.0003044104,0.0004345887,0.0002475159,0.0002541133,0.001165358,0.0004277888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003162098,"about_ca_system_score_gemma":0.0003002288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001288471,"about_ca_topic_score_gemma":0.001198629,"domain_scores_codex":[0.999743,0.00004644131,0.00002856515,0.00004820399,0.00006358195,0.00007002638],"domain_scores_gemma":[0.9998059,0.00001090216,0.00006310194,0.00001691848,0.00001406178,0.00008923795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009779622,0.0004390905,0.0001718525,0.00006216333,0.000016691,0.00009066793,0.00001351567,0.00008834028,0.9963731,0.00005794884,0.0001066088,0.001602085],"study_design_scores_gemma":[0.0005576162,0.01512814,0.01096498,0.00005691766,0.0001169421,0.0008112061,0.0001532149,0.002412671,0.9659978,0.0001286491,0.003641559,0.00003031835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938262,0.001787915,0.00175121,0.0003038835,0.0001250068,0.00007831542,0.0009087949,0.0002667989,0.0009518791],"genre_scores_gemma":[0.9922964,0.001307557,0.002310876,0.0001383828,0.00002450792,0.0001261083,0.0008940944,0.0000388088,0.00286327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00164152,"threshold_uncertainty_score":0.005491376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008536794863140022,"score_gpt":0.2218365023327193,"score_spread":0.2132997074695793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}