{"id":"W3007385511","doi":"10.1371/journal.pone.0229030","title":"Interaction of field realistic doses of clothianidin and Varroa destructor parasitism on adult honey bee (Apis mellifera L.) health and neural gene expression, and antagonistic effects on differentially expressed genes","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Ontario Ministry of Agriculture, Food and Rural Affairs; Ministry of Agriculture, Food and Rural Affairs; Génome Québec","keywords":"Varroa destructor; Clothianidin; Varroa; Biology; Destructor; Neonicotinoid; Honey bee; KEGG; Pollinator; Gene expression; Gene; Genetics; Zoology; Botany; Imidacloprid; Pesticide; Ecology; Pollination; Mite; Thiamethoxam","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005849987,0.0001290423,0.0003078342,0.00001838049,0.0001136501,0.00003461082,0.00007425386,0.00006748396,0.0000353349],"category_scores_gemma":[0.0003297863,0.00006111372,0.00002231809,0.00007605051,0.00005868518,0.00004939414,0.00004907825,0.0001325357,5.432789e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000618124,"about_ca_system_score_gemma":0.000009147728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004287346,"about_ca_topic_score_gemma":0.00004409452,"domain_scores_codex":[0.9989519,0.0001719455,0.0002141751,0.0002546922,0.0002393716,0.0001679583],"domain_scores_gemma":[0.9986203,0.0009620946,0.0001168117,0.00004046794,0.00006481331,0.0001954603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005645973,0.0001531793,0.007879991,0.000455864,0.00002312307,0.000004730954,0.0003331086,8.679465e-7,0.9835393,0.00008185045,0.00002645767,0.006936912],"study_design_scores_gemma":[0.0003043778,0.003551915,0.03423356,0.0003957077,0.00002349338,0.000002359188,0.00005904481,0.0004510149,0.9606898,0.0001859202,0.000001139449,0.0001017159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977209,0.0003765665,0.000006658313,0.001493866,0.00002352342,0.0002734137,0.00008124574,0.00001615619,0.000007697197],"genre_scores_gemma":[0.9978708,0.001374356,0.0001699631,0.0003853886,0.0001476756,0.00001087668,0.00003408689,0.000002074659,0.000004801492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02635356,"threshold_uncertainty_score":0.2492145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05120695462418805,"score_gpt":0.2624492196741823,"score_spread":0.2112422650499943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}