{"id":"W3007385511","doi":"10.1371/journal.pone.0229030","title":"Interaction of field realistic doses of clothianidin and Varroa destructor parasitism on adult honey bee (Apis mellifera L.) health and neural gene expression, and antagonistic effects on differentially expressed genes","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Ontario Ministry of Agriculture, Food and Rural Affairs; Ministry of Agriculture, Food and Rural Affairs; Génome Québec","keywords":"Varroa destructor; Clothianidin; Varroa; Biology; Destructor; Neonicotinoid; Honey bee; KEGG; Pollinator; Gene expression; Gene; Genetics; Zoology; Botany; Imidacloprid; Pesticide; Ecology; Pollination; Mite; Thiamethoxam","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006019539,0.00018278,0.0002361935,0.0001076353,0.00007406741,0.0001763803,0.0000839938,0.0001945887,0.0006377651],"category_scores_gemma":[0.0001161785,0.00007633703,0.0001467598,0.00005716578,0.0001252104,0.0001055645,0.0001351996,0.0002622258,0.00005526971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001737846,"about_ca_system_score_gemma":0.00009410389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007217412,"about_ca_topic_score_gemma":0.001428406,"domain_scores_codex":[0.9999126,0.00001500799,0.000006342905,0.00003206603,0.00001698086,0.00001704768],"domain_scores_gemma":[0.9999217,0.00001789105,0.00002406304,0.000007210524,0.00001083648,0.0000182379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005812191,0.00009267942,0.002741917,0.00004319688,0.00001638819,0.00004216461,0.00003449603,0.00008926214,0.9944835,0.00001378732,0.00003248985,0.001828859],"study_design_scores_gemma":[0.00005625243,0.008403718,0.3519157,0.00001811961,0.0001368577,0.000375814,0.0004445596,0.002188704,0.6340153,0.00008319409,0.002341538,0.00002021809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994264,0.0001854807,0.00008516744,0.00002264255,0.000006038323,0.000006335643,0.00007222375,0.000005331754,0.0001904404],"genre_scores_gemma":[0.9985297,0.0001648102,0.0002808099,0.0000444924,0.000004355602,0.00001461545,0.0001345982,0.000001942527,0.0008246184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007217412,"threshold_uncertainty_score":0.002133548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05120695462418805,"score_gpt":0.2624492196741823,"score_spread":0.2112422650499943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}