{"id":"W3007405904","doi":"10.1038/s41375-020-0777-1","title":"CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm","year":2020,"lang":"en","type":"article","venue":"Leukemia","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Agence Nationale de la Recherche","keywords":"Interleukin-3 receptor; CD28; Plasmacytoid dendritic cell; Cancer research; Biology; Effector; Immunotherapy; Immunology; T cell; Immune system; Antigen; Dendritic cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001722467,0.0002882171,0.0005222853,0.0001872127,0.00005475023,0.0000440852,0.0002819137,0.0002109149,0.002602306],"category_scores_gemma":[0.0001477299,0.0002864511,0.0001576868,0.0006276944,0.0001163918,0.00007949129,0.0001307292,0.0009678453,0.002142077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000890978,"about_ca_system_score_gemma":0.0007680799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002135207,"about_ca_topic_score_gemma":0.0001315041,"domain_scores_codex":[0.9975569,0.00009890845,0.0004200693,0.000572512,0.0006133632,0.0007382621],"domain_scores_gemma":[0.9985181,0.0003500716,0.00005593002,0.0004367931,0.00007278906,0.0005663313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006432724,0.000104413,0.01165609,0.0005258308,0.00004434933,0.001852018,0.001746135,0.001329282,0.9724804,0.00003626928,0.007794094,0.001787809],"study_design_scores_gemma":[0.01449614,0.001321245,0.009743106,0.0003013346,0.0001462707,0.0001985523,0.0009059808,0.03018155,0.819465,0.0001135769,0.1222792,0.0008480891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740409,0.0002177655,0.00008282348,0.001002747,0.0002531062,0.0006016936,0.00001513701,0.0001301221,0.02365575],"genre_scores_gemma":[0.984994,0.0001432602,0.0003416449,0.001937475,0.0004783893,0.00003718387,0.00002617217,0.0000914718,0.0119504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1530154,"threshold_uncertainty_score":0.9999588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02169849098013783,"score_gpt":0.2684581499687368,"score_spread":0.246759658988599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}