{"id":"W3007415534","doi":"10.1097/wnr.0000000000001411","title":"LncRNA cancer susceptibility candidate (CASC7) upregulates phosphatase and tensin homolog by downregulating miR-10a to inhibit neuroblastoma cell proliferation","year":2020,"lang":"en","type":"article","venue":"Neuroreport","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Tensin; Neuroblastoma; Downregulation and upregulation; Cancer research; microRNA; Biology; Cell growth; Phosphatase; Cancer; Cell biology; Cell culture; Signal transduction; PTEN; Gene; Phosphorylation; PI3K/AKT/mTOR pathway; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002049112,0.0003162792,0.0002724826,0.00005214236,0.0001610847,0.00009552635,0.0001837291,0.0001988842,0.00007209313],"category_scores_gemma":[0.0002663498,0.0003267415,0.00008506559,0.0002831546,0.0001000797,0.00001543135,0.000377846,0.0002768468,0.00001278315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003626664,"about_ca_system_score_gemma":0.0002226529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003084278,"about_ca_topic_score_gemma":0.0002094717,"domain_scores_codex":[0.9974213,0.0001199404,0.0004597225,0.001145006,0.0003644291,0.0004896058],"domain_scores_gemma":[0.9986226,0.00001298273,0.0001739481,0.000524775,0.0001987044,0.000467023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002916111,0.0000476494,0.001251558,0.00005602154,0.00002392504,0.00011564,0.00008013338,0.0006169704,0.9793403,0.000003089495,0.01636004,0.001813111],"study_design_scores_gemma":[0.0006346945,0.0007404687,0.001470309,0.00001489516,0.00003019256,0.00009459199,0.00001878529,0.001270343,0.9827545,0.00001092049,0.01264061,0.0003197077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944559,0.0007529677,0.001378777,0.001974306,0.0001320721,0.0009189884,0.000172409,0.00005751015,0.0001570314],"genre_scores_gemma":[0.9957233,0.0001044065,0.0003484878,0.00278655,0.0001794978,0.00009048294,0.000322019,0.00007227463,0.0003729751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00371943,"threshold_uncertainty_score":0.9999185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009542040861035167,"score_gpt":0.2541426766109927,"score_spread":0.2446006357499576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}