{"id":"W3007545260","doi":"10.1093/jcag/gwz047.017","title":"A18 BUILDING BETTER ENTEROIDS: A NOVEL STRATEGY FOR ENRICHING SECRETORY EPITHELIAL CELL SUBTYPES","year":2020,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Burnaby Hospital; BC Children's Hospital","funders":"","keywords":"Wnt signaling pathway; Enteroendocrine cell; Biology; Cell biology; Goblet cell; Intestinal epithelium; Flow cytometry; Secretion; Mucus; Enterocyte; Immunology; Epithelium; Signal transduction; Endocrinology; Hormone; Endocrine system; Small intestine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005408083,0.000095297,0.0002254322,0.00006407894,0.00009169292,0.00001394609,0.0002427795,0.0001739672,0.000006034312],"category_scores_gemma":[0.0001895009,0.00007521921,0.0002004469,0.00004188209,0.00002762279,0.000006916378,0.00002513181,0.0001993783,7.442227e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001874892,"about_ca_system_score_gemma":0.0003891183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003748115,"about_ca_topic_score_gemma":0.01601188,"domain_scores_codex":[0.9989148,0.000156147,0.0004096426,0.0001133894,0.0001305078,0.0002755146],"domain_scores_gemma":[0.9985493,0.00002514273,0.0008951876,0.00007759705,0.0002575398,0.00019519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006235891,0.00005956913,0.3851579,0.00009148409,0.0004378451,0.000003320836,0.0003618913,0.00166287,0.5980045,0.00006787846,0.01339744,0.000131722],"study_design_scores_gemma":[0.03229574,0.02608485,0.5191029,0.0005058622,0.001126401,0.0003700413,0.001424853,0.001509515,0.1259562,0.0004882138,0.2901145,0.001021011],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863083,0.00005876397,0.002493673,0.01017025,0.0005624039,0.0001522906,0.0001426098,0.000001448828,0.0001102971],"genre_scores_gemma":[0.9948387,0.00001453005,0.0004584044,0.004009411,0.0005277396,0.000001775349,0.000007560456,0.00001364393,0.0001282856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4720483,"threshold_uncertainty_score":0.8935003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134719309661925,"score_gpt":0.2310528930534437,"score_spread":0.2197056999568245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}